Product nameAnti-Neurturin antibody
See all Neurturin primary antibodies
DescriptionSheep polyclonal to Neurturin
SpecificityCross reactivity: This antibody is known to react with human, mouse, rat and other rodents. Cross reactivity with other species has not been tested. No cross reactivity with Glial cell line-derived Neurotrophic Factor
Tested applicationsSuitable for: Dot blot, ELISA, IHC-Fr, WBmore details
Species reactivityReacts with: Human
Recombinant full length protein (Human).
General notesThis antibody has been used for immunohistochemistry and immunoblotting.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Our Abpromise guarantee covers the use of ab6208 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Western Blot: 1/3,000
1 site ELISA: 1/2,000-3,000
Biological Inhibition: Not tested.
FunctionSupports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
Involvement in diseaseDefects in NRTN are a cause of Hirschsprung disease (HSCR) [MIM:142623]. In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.
Sequence similaritiesBelongs to the TGF-beta family. GDNF subfamily.
- Information by UniProt
- Neurturin antibody
- Neurturin precursor antibody
- NRTN antibody
ab6208 has not yet been referenced specifically in any publications.