Anti-NHERF-2/SIP-1 antibody [32B6] (ab151443)

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Overview

  • Product name

    Anti-NHERF-2/SIP-1 antibody [32B6]
    See all NHERF-2/SIP-1 primary antibodies

  • Description

    Mouse monoclonal [32B6] to NHERF-2/SIP-1

  • Host species

    Mouse

  • Tested applications

    Suitable for: WB, IPmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat

  • Immunogen

    Full length protein corresponding to Human NHERF-2/SIP-1.
    Sequence:

    MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAAL RAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQ LTCTEEMAQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGPLRELRPR LCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVN GQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEG PLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGL HLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • General notes

    Previously labelled as SLC9A3R2. 

Properties

Applications

Our Abpromise guarantee covers the use of ab151443 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100. Predicted molecular weight: 37 kDa.
IP Use at an assay dependent concentration.

Target

  • Function

    Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus.

  • Tissue specificity

    Widely expressed.

  • Sequence similarities

    Contains 2 PDZ (DHR) domains.

  • Cellular localization

    Endomembrane system. Nucleus. Apical cell membrane. Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity). Nuclear, in a punctate pattern.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • E3KARP antibody
    • HGNC:11076 antibody
    • Isoform 3 regulator 2 antibody
    • Isoform 3 regulatory factor 2 antibody
    • MGC104639 antibody
    • Na(+)/H(+) exchange regulatory cofactor NHE RF2 antibody
    • Na(+)/H(+) exchange regulatory cofactor NHE-RF2 antibody
    • NHE3 kinase A regulatory protein antibody
    • NHE3 kinase A regulatory protein E3KARP antibody
    • NHE3 regulatory factor 2 antibody
    • NHE3RF2 antibody
    • NHERF 2 antibody
    • NHERF-2 antibody
    • NHERF2 antibody
    • NHRF2_HUMAN antibody
    • OCTS2 antibody
    • SIP 1 antibody
    • SIP-1 antibody
    • SIP1 antibody
    • Slc9a3r2 antibody
    • Sodium hydrogen exchanger regulatory factor 2 antibody
    • Sodium-hydrogen exchanger regulatory factor 2 antibody
    • Sodium/hydrogen exchanger antibody
    • Sodium/hydrogen exchanger regulatory factor 2 antibody
    • Solute carrier family 9 (sodium/hydrogen exchanger) antibody
    • Solute carrier family 9 (sodium/hydrogen exchanger) isoform 3 regulator 2 antibody
    • Solute carrier family 9 (sodium/hydrogen exchanger) isoform 3 regulatory factor 2 antibody
    • Solute carrier family 9 (sodium/hydrogen exchanger) member 3 regulator 2 antibody
    • Solute carrier family 9 isoform 3 regulator 2 antibody
    • Solute carrier family 9 isoform A3 regulatory factor 2 antibody
    • SRY interacting protein 1 antibody
    • SRY-interacting protein 1 antibody
    • TKA 1 antibody
    • TKA-1 antibody
    • TKA1 antibody
    • Tyrosine kinase activator protein 1 antibody
    see all

Images

  • Western blot - Anti-NHERF-2/SIP-1 antibody [32B6] (ab151443)
    Western blot - Anti-NHERF-2/SIP-1 antibody [32B6] (ab151443)
    Anti-NHERF-2/SIP-1 antibody [32B6] (ab151443) at 1/100 dilution + HaCat Human keratinocyte cells

    Predicted band size: 37 kDa

References

ab151443 has not yet been referenced specifically in any publications.

Publishing research using ab151443? Please let us know so that we can cite the reference in this datasheet.

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