Overview

  • Product name
    Anti-Nicotinic Acetylcholine Receptor alpha 5 antibody
    See all Nicotinic Acetylcholine Receptor alpha 5 primary antibodies
  • Description
    Goat polyclonal to Nicotinic Acetylcholine Receptor alpha 5
  • Host species
    Goat
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Chicken, Hamster, Cow, Pig, Chimpanzee, Monkey, Gorilla, Elephant
  • Immunogen

    Synthetic peptide, corresponding to internal sequence amino acids 369-380 of Human Nicotinic Acetylcholine Receptor alpha 5 (NP_000736.2).

  • Positive control
    • KELLY lysate; Human Colon, Submucosal Plexus tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab166718 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 53 kDa.
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • Sequence similarities
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-5/CHRNA5 sub-subfamily.
  • Cellular localization
    Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Acetylcholine receptor nicotinic alpha 5 (neuronal) antibody
    • ACHA5_HUMAN antibody
    • AChR antibody
    • Cholinergic receptor neuronal nicotinic alpha polypeptide 5 antibody
    • Cholinergic receptor nicotinic alpha 5 antibody
    • Cholinergic receptor nicotinic alpha polypeptide 5 antibody
    • CHRNA 5 antibody
    • CHRNA5 antibody
    • LNCR2 antibody
    • NACHRA 5 antibody
    • NACHRA5 antibody
    • Neuronal acetylcholine receptor subunit alpha 5 antibody
    • Neuronal acetylcholine receptor subunit alpha-5 antibody
    • Neuronal nicotinic acetylcholine receptor alpha 5 subunit antibody
    • Neuronal nicotinic acetylcholine receptor, alpha5 subunit antibody
    • OTTHUMP00000185019 antibody
    see all

Images

  • Anti-Nicotinic Acetylcholine Receptor alpha 5 antibody (ab166718) at 1 µg/ml + Kelly cell lysate (in RIPA buffer) at 35 µg

    Developed using the ECL technique.

    Predicted band size: 53 kDa

  • Immunohistochemical analysis of Formalin-Fixed, Paraffin-Embedded Human Colon, Submucosal Plexus tissue labeling Nicotinic Acetylcholine Receptor alpha 5 with ab166718 at 3.75 µg/ml.

References

ab166718 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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