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Goat polyclonal to Nicotinic Acetylcholine Receptor alpha 5
HumanPredicted to work with:
Horse, Chicken, Hamster, Cow, Pig, Chimpanzee, Monkey, Gorilla, Elephant
Synthetic peptide, corresponding to internal sequence amino acids 369-380 of Human Nicotinic Acetylcholine Receptor alpha 5 (NP_000736.2).
- KELLY lysate; Human Colon, Submucosal Plexus tissue.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 53 kDa.
||Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-5/CHRNA5 sub-subfamily.
Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
Information by UniProt
- Acetylcholine receptor nicotinic alpha 5 (neuronal) antibody
- ACHA5_HUMAN antibody
- AChR antibody
Western blot - Anti-Nicotinic Acetylcholine Receptor alpha 5 antibody (ab166718)
Anti-Nicotinic Acetylcholine Receptor alpha 5 antibody (ab166718) at 1 µg/ml + Kelly cell lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 53 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Nicotinic Acetylcholine Receptor alpha 5 antibody (ab166718)
Immunohistochemical analysis of Formalin-Fixed, Paraffin-Embedded Human Colon, Submucosal Plexus tissue labeling Nicotinic Acetylcholine Receptor alpha 5 with ab166718 at 3.75 µg/ml.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"