Overview

  • Product name

    Anti-Nicotinic Acetylcholine Receptor beta 2/CHRNB2 antibody
    See all Nicotinic Acetylcholine Receptor beta 2/CHRNB2 primary antibodies
  • Description

    Rabbit polyclonal to Nicotinic Acetylcholine Receptor beta 2/CHRNB2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Rat, Chicken, Cow, Human, Xenopus laevis, Xenopus tropicalis
  • Immunogen

    Recombinant fragment corresponding to Human Nicotinic Acetylcholine Receptor beta 2/CHRNB2 aa 25-273.
    Database link: P17787

  • Positive control

    • Mouse brain whole cell lysate
  • General notes

     This product was previously labelled as Nicotinic Acetylcholine Receptor beta 2

     

Properties

Applications

Our Abpromise guarantee covers the use of ab151785 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 57 kDa.

Target

  • Function

    After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • Involvement in disease

    Defects in CHRNB2 are the cause of nocturnal frontal lobe epilepsy type 3 (ENFL3) [MIM:605375]. ENFL3 is an autosomal dominant epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements.
  • Sequence similarities

    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-2/CHRNB2 sub-subfamily.
  • Cellular localization

    Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Acetylcholine receptor beta 2 neural antibody
    • ACHB2_HUMAN antibody
    • ACHN antibody
    • AChR antibody
    • Acrb 2 antibody
    • Acrb2 antibody
    • b2 nAchR antibody
    • Cholinergic receptor nicotinic beta 2 antibody
    • Cholinergic receptor nicotinic beta polypeptide 2 antibody
    • Cholinergic receptor nicotinic beta polypeptide 2 neuronal antibody
    • cholinergic receptor, nicotinic, beta 2 (neuronal) antibody
    • Chrnb2 antibody
    • EFNL 3 antibody
    • EFNL3 antibody
    • nAChRB2 antibody
    • Neuronal acetylcholine receptor protein beta 2 chain precursor antibody
    • Neuronal acetylcholine receptor protein subunit beta 2 antibody
    • Neuronal acetylcholine receptor subunit beta-2 antibody
    • Neuronal nicotinic acetylcholine receptor beta 2 antibody
    see all

Images

  • Anti-Nicotinic Acetylcholine Receptor beta 2/CHRNB2 antibody (ab151785) at 1/5000 dilution + Mouse brain whole cell lysate at 50 µg

    Predicted band size: 57 kDa



    7.5% SDS PAGE

References

ab151785 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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