Overview

  • Product name
    Nimodipine, L-type Ca2+ channel blocker
  • Description
    L-type Ca2+ channel blocker
  • Biological description
    L-type Ca2+ channel blocker. Potent cerebrovasodilator. Cognitive enhancer. More lipophilic than nifedipine (ab120135).
  • Purity
    > 98%
  • General notes

    Nimodipine is light sensitive and it is recommended that the compound is protected from light.

  • CAS Number
    66085-59-4
  • Chemical structure
    Chemical Structure

Properties

Applications

Our Abpromise guarantee covers the use of ab120138 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies Use at an assay dependent concentration.

Images

  • ab2770 staining aryl hydrocarbon receptor in MDA-MB-231 cells treated with nimodipine (ab120138), by ICC/IF. Increase in aryl hydrocarbon receptor expression correlates with increased concentration of nimodipine, as described in literature.
    The cells were incubated at 37°C for 6h in media containing different concentrations of ab120138 (nimodipine) in DMSO, fixed with 100% methanol for 5 minutes at -20°C and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab2770 (1/100 dilution) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-mouse polyclonal antibody (ab96879) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.

References

This product has been referenced in:
See all 2 Publications for this product

Customer reviews and Q&As

Answer

Thank you for contacting us. We can confirm that ab120138 (formerly Asc-138) Nimodipine is a racemic mixture. I hope this helps, please let me know if you need any additional information.

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