Key features and details
- Rabbit polyclonal to NIPSNAP1
- Suitable for: ICC/IF, IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-NIPSNAP1 antibody
See all NIPSNAP1 primary antibodies
DescriptionRabbit polyclonal to NIPSNAP1
Tested applicationsSuitable for: ICC/IF, IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide (Human) of 18 amino acids from near the C-terminus.
- Human Brain Tissue Lysate
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab67302 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|IHC-P||Use a concentration of 2.5 µg/ml.|
|WB||Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).|
RelevanceNIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.
- NIPSNAP 1 antibody
- Nipsnap homolog 1 (C. elegans) antibody
- Protein NipSnap homolog 1 antibody
Lane 1 : Anti-NIPSNAP1 antibody (ab67302) at 0.5 µg/ml
Lane 2 : Anti-NIPSNAP1 antibody (ab67302) at 1 µg/ml
All lanes : Human brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 33 kDa
Observed band size: 33 kDa
ab67302 at 2.5 µg/ml staining NIPSNAP1 in human prostate tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).
Immunofluorescence of NIPSNAP in Human Brain cells using ab67302 at 20 ug/ml.
ab67302 has been referenced in 1 publication.
- Uthaiah RC & Hudspeth AJ Molecular anatomy of the hair cell's ribbon synapse. J Neurosci 30:12387-99 (2010). PubMed: 20844134