Key features and details
- Rabbit polyclonal to NIPSNAP1
- Suitable for: WB, ICC/IF, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-NIPSNAP1 antibody
See all NIPSNAP1 primary antibodies
DescriptionRabbit polyclonal to NIPSNAP1
Tested applicationsSuitable for: WB, ICC/IF, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Human
a 19 amino acid synthetic peptide from near the center of human NIPSNAP.
- human brain tissue lysate
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab67324 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).|
|ICC/IF||Use a concentration of 20 µg/ml.|
|IHC-P||Use a concentration of 2.5 µg/ml.|
RelevanceNIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.
- NIPSNAP 1 antibody
- Nipsnap homolog 1 (C. elegans) antibody
- Protein NipSnap homolog 1 antibody
Immunofluorescence of NIPSNAP1 in Human brain tissue with ab67324 at 20 ug/mL.
Lane 1 : Anti-NIPSNAP1 antibody (ab67324) at 0.5 µg/ml
Lane 2 : Anti-NIPSNAP1 antibody (ab67324) at 1 µg/ml
All lanes : human brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 33 kDa
Observed band size: 33 kDa
ab67324 at 2.5 µg/ml staining NIPSNAP1 in human prostate tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).
ab67324 has not yet been referenced specifically in any publications.