Overview

  • Product name

  • Description

    Rabbit polyclonal to NISCH
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human NISCH aa 500-700.
    Database link: Q9Y2I1

  • Positive control

    • IHC-P: Human brain and adrenal gland tissues.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab229970 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.

Target

  • Relevance

    Mouse Nischarin (NISCH) has been shown to interact with the alpha-5 subunit of integrin and inhibit cell migration. Its human homologue (imidazoline receptor antisera-selected (IRAS)), contains an NH2-terminal extension and is a larger protein of 1504 amino acids consisting of an NH2-terminal PX domain, 5 putative leucine-rich repeats, a predicted coiled-coil domain, and a long COOH-terminal region. It has the ability to homo-oligomerize via its coiled-coil region. The PX domain of IRAS is essential for association with phosphatidylinositol 3-phosphate-enriched endosomal membranes. NISCH may serve as a functional imidazoline I1-receptor.
  • Cellular localization

    Cell membrane. Cytoplasm. Early endosome. Recycling endosome.
  • Database links

  • Alternative names

    • FLJ14425 antibody
    • FLJ40413 antibody
    • FLJ90519 antibody
    • I 1 antibody
    • I 1 receptor candidate protein antibody
    • I1R candidate protein antibody
    • Imidazoline 1 receptor candidate protein antibody
    • Imidazoline receptor 1 antibody
    • Imidazoline receptor antisera selected antibody
    • Imidazoline receptor antisera selected protein antibody
    • Imidazoline receptor candidate antibody
    • IR1 antibody
    • IRAS antibody
    • KIAA0975 antibody
    • Nischarin antibody
    see all

Images

  • Paraffin-embedded human adrenal gland tissue stained for NISCH using ab229970 at 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human brain tissue stained for NISCH using ab229970 at 1/100 dilution in immunohistochemical analysis.

References

ab229970 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab229970.
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