Overview

  • Product name
    Nithiamide
  • Description
    Non-5-nitroimidazole antiparasitic agent
  • Biological description
    Non-5-nitroimidazole antiparasitic agent. Shows antidysentery effects in vivo. Orally active.
  • Purity
    > 99%

Properties

  • Chemical name
    N-(5-Nitro-1,3-thiazol-2-yl)acetamide
  • Molecular weight
    187.18
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C5H5N3O3S
  • CAS Number
    140-40-9
  • PubChem identifier
    8798
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    CC(=O)NC1=NC=C(S1)[N+](=O)[O-]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:
  • Goodhew EB & Secor WE Drug library screening against metronidazole-sensitive and metronidazole-resistant Trichomonas vaginalis isolates. Sex Transm Infect 89:479-84 (2013). Read more (PubMed: 23794105) »
  • Raynaud JP  et al. A swine dysentery model for evaluation of drug prophylaxis: efficacy of various drugs in the control of swine dysentery. Am J Vet Res 42:51-3 (1981). Read more (PubMed: 7224318) »
  • Layton HW  et al. Efficacy of nithiamide in preventing and treating swine dysentery in experimentally inoculated pigs. Am J Vet Res 38:627-31 (1977). Read more (PubMed: 879561) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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