Product nameAnti-Nitro tyrosine antibody
See all Nitro tyrosine primary antibodies
DescriptionGoat polyclonal to Nitro tyrosine
SpecificitySpecifically binds to nitrate LDL, and other nitrated proteins.
Tested applicationsSuitable for: ELISA, WBmore details
Synthetic peptide - Nitrotyrosine (NY) modified Protein
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 0.2% PBS, 0.435% Sodium chloride
Concentration information loading...
Purification notesPurified by nitrated protein-SepharoseTM affinity column.
Our Abpromise guarantee covers the use of ab27628 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: range: 1/5000 to 1/40000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceNitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic placques.
- NO tyrosine antibody
- nTyr antibody
ab27628 has not yet been referenced specifically in any publications.