Key features and details
- Rabbit polyclonal to Nitro tyrosine
- Suitable for: WB, ELISA
- Isotype: IgG
Product nameAnti-Nitro tyrosine antibody
See all Nitro tyrosine primary antibodies
DescriptionRabbit polyclonal to Nitro tyrosine
SpecificityThis antibody reacts with free and bound nitrotyrosine. There is no cross reaction with free or bound tyrosine
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivitynot applicable
Chemical/ Small Molecule conjugated to KLH: Nitrotyrosine
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: none.
Concentration information loading...
Our Abpromise guarantee covers the use of ab42789 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/200 - 1/2000. Predicted molecular weight: 1 kDa.|
|ELISA||1/5000 - 1/20000.|
RelevanceNitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic placques.
- NO tyrosine antibody
- nTyr antibody
ab42789 has been referenced in 12 publications.
- Trias E et al. Emergence of Microglia Bearing Senescence Markers During Paralysis Progression in a Rat Model of Inherited ALS. Front Aging Neurosci 11:42 (2019). PubMed: 30873018
- Lee JA et al. Age Induced Nitroso-Redox Imbalance Leads to Subclinical Hypogonadism in Male Mice. Front Endocrinol (Lausanne) 10:190 (2019). PubMed: 30984111
- Caielli S et al. A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate. Nat Med 25:75-81 (2019). PubMed: 30478422
- Rahman MS et al. Effect of antioxidants on BPA-induced stress on sperm function in a mouse model. Sci Rep 9:10584 (2019). PubMed: 31332285
- Soni H et al. Early onset of renal oxidative stress in small for gestational age newborn pigs. Redox Rep 24:10-16 (2019). PubMed: 30907266