Overview

  • Product name
    Anti-Nitro tyrosine antibody (Biotin)
    See all Nitro tyrosine primary antibodies
  • Description
    Goat polyclonal to Nitro tyrosine (Biotin)
  • Host species
    Goat
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Immunogen

    Chemical/ Small Molecule (Nitrotyrosine)

Properties

Applications

Our Abpromise guarantee covers the use of ab27646 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notes
    ELISA: Range 1/5000 - 1/40000.
    WB: Range 1/5000 - 1/40000. Predicted molecular weight: na kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      Nitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic placques.
    • Alternative names
      • NO tyrosine antibody
      • nTyr antibody

    References

    This product has been referenced in:
    • Ferreira I  et al. Nitrated nucleosome levels and neuropsychiatric events in systemic lupus erythematosus; a multi-center retrospective case-control study. Arthritis Res Ther 19:287 (2017). Read more (PubMed: 29273092) »
    • Croca S  et al. Serum nitrated nucleosome levels in patients with systemic lupus erythematosus: a retrospective longitudinal cohort study. Arthritis Res Ther 16:R48 (2014). ELISA ; Human . Read more (PubMed: 24502558) »

    See all 2 Publications for this product

    Customer reviews and Q&As

    Thank you for contacting us.

    The ab27628 Anti-Nitro tyrosine antibody is the one you are looking for:

    https://www.abcam.com/index.html?datasheet=27628 (or use the following: https://www.abcam.com/index.html?datasheet=27628).

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