Nitroso(acetoxymethyl)methylamine (Dmn-oac), carcinogenic agent (ab143671)

Overview

  • Product name

    Nitroso(acetoxymethyl)methylamine (Dmn-oac), carcinogenic agent
  • Description

    Potent carcinogenic agent
  • Biological description

    Potent carcinogenic agent. Induces methylation and pyridyloxobutylation of DNA. Shows rapid tumorigenic effects in vivo.
  • Purity

    > 98%
  • CAS Number

    56856-83-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Proulx LI  et al. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a component of tobacco smoke, modulates mediator release from human bronchial and alveolar epithelial cells. Clin Exp Immunol 140:46-53 (2005). Read more (PubMed: 15762874) »
  • Cloutier JF  et al. Treatment of human cells with N-Nitroso(acetoxymethyl)methylamine: distribution patterns of piperidine-sensitive DNA damage at the nucleotide level of resolution are related to the sequence context. Chem Res Toxicol 12:840-9 (1999). Read more (PubMed: 10490506) »
  • Habs M  et al. Effect of disulfiram on acetoxymethyl-methyl-nitrosamine-induced tumors in rats. Oncology 38:18-22 (1981). Read more (PubMed: 7443171) »

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