Key features and details
- Goat polyclonal to NK-1R
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-NK-1R antibody
See all NK-1R primary antibodies
DescriptionGoat polyclonal to NK-1R
SpecificityThis antibody is expected to recognise both reported isoforms (NP_001049.1 and NP_056542.1).
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Chicken, Guinea pig, Dog
- Human Testes lysate.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% Tris buffered saline, 0.5% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab61705 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight isoform 2: 35 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionThis is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- Neurokinin 1 antibody
- Neurokinin 1 Receptor antibody
- NK 1 receptor antibody
ab61705 has been referenced in 1 publication.
- Liu X et al. Antagonism of NK-1R using aprepitant suppresses inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes. Artif Cells Nanomed Biotechnol 47:1628-1634 (2019). PubMed: 31010320