Key features and details
- Rabbit polyclonal to NK-1R - Extracellular domain
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-NK-1R antibody - Extracellular domain
See all NK-1R primary antibodies
DescriptionRabbit polyclonal to NK-1R - Extracellular domain
SpecificityBLAST analysis of the peptide immunogen showed no homology with other human proteins.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Rabbit, Horse, Guinea pig, Cow, Dog, Monkey
Synthetic peptide corresponding to Human NK-1R (extracellular). 16 amino acid peptide from 2nd extracellular domain.
Database link: P25103
- IHC-P: Human brain neurons, brain glioblastoma and lung adenocarcinoma tissue.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.099% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab219600 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 2 - 4 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
FunctionThis is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- Neurokinin 1 antibody
- Neurokinin 1 Receptor antibody
- NK 1 receptor antibody
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain neuron tissue labeling NK-1R with ab219600 at 4 µg/mL.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain glioblastoma tissue labeling NK-1R with ab219600 at 4 µg/mL.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human lung adenocarcinoma tissue labeling NK-1R with ab219600 at 4 µg/mL.
ab219600 has not yet been referenced specifically in any publications.