Overview

  • Product name

    Anti-NK-1R antibody - Extracellular domain
    See all NK-1R primary antibodies
  • Description

    Rabbit polyclonal to NK-1R - Extracellular domain
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rabbit, Horse, Guinea pig, Cow, Dog, Monkey
  • Immunogen

    Synthetic peptide corresponding to Human NK-1R (extracellular). 16 amino acid peptide from 2nd extracellular domain.
    Database link: P25103

  • Positive control

    • IHC-P: Human brain neurons, brain glioblastoma and lung adenocarcinoma tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.099% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab219600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 2 - 4 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Neurokinin 1 antibody
    • Neurokinin 1 Receptor antibody
    • NK 1 receptor antibody
    • NK 1R antibody
    • NK-1 receptor antibody
    • NK-1R antibody
    • NK1 receptor antibody
    • NK1R antibody
    • NK1R_HUMAN antibody
    • NKIR antibody
    • SPR antibody
    • Substance P receptor antibody
    • Substance-P receptor antibody
    • TAC 1R antibody
    • TAC1R antibody
    • Tachykinin 1 receptor (substance P receptor neurokinin 1 receptor) antibody
    • Tachykinin receptor 1 (substance P receptor neurokinin 1 receptor) antibody
    • Tachykinin receptor 1 antibody
    • TACR1 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain neuron tissue labeling NK-1R with ab219600 at 4 µg/mL.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain glioblastoma tissue labeling NK-1R with ab219600 at 4 µg/mL.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human lung adenocarcinoma tissue labeling NK-1R with ab219600 at 4 µg/mL.

References

ab219600 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab219600.
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