Overview

  • Product name

  • Description

    Rabbit polyclonal to NK-3R
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human NK-3R aa 405-435 (C terminal) conjugated to keyhole limpet haemocyanin.
    (Peptide available as ab176476)

  • Positive control

    • K562 cell line lysates.
  • General notes

    Protein previously labeled as Neurokinin 3 Receptor NK3.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab123303 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab123303 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 52 kDa.

Target

  • Function

    This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.
  • Involvement in disease

    Hypogonadotropic hypogonadism 11 with or without anosmia
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications

    The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • MGC148060 antibody
    • MGC148061 antibody
    • Neurokinin B receptor antibody
    • Neurokinin beta receptor antibody
    • Neuromedin K Receptor antibody
    • Neuromedin-K receptor antibody
    • NK 3 receptor antibody
    • NK 3R antibody
    • NK-3 receptor antibody
    • NK-3R antibody
    • NK3 receptor antibody
    • NK3R antibody
    • NK3R_HUMAN antibody
    • NKR antibody
    • TAC 3R antibody
    • TAC3R antibody
    • TAC3RL antibody
    • Tachykinin receptor 3 antibody
    • TACR 3 antibody
    • Tacr3 antibody
    see all

Images

  • Anti-NK-3R antibody (ab123303) at 1/100 dilution + K562 cell line lysates at 35 µg

    Predicted band size: 52 kDa

References

This product has been referenced in:

  • Veldkamp MW  et al. Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel. Nat Commun 9:4357 (2018). Read more (PubMed: 30341287) »
See 1 Publication for this product

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