The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-NK-3R antibody (ab124025)
Protein previously labeled as Neurokinin 3 Receptor NK3.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C.
Neurokinin B receptor
Neurokinin beta receptor
Neuromedin K Receptor
NK 3 receptor
Tachykinin receptor 3
This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.
Involvement in disease
Hypogonadotropic hypogonadism 11 with or without anosmia
Belongs to the G-protein coupled receptor 1 family.
The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue.