Recombinant
RabMAb

Recombinant Anti-NK-p44 antibody [EPR5060(2)] - Low endotoxin, Azide free (ab246801)

Overview

  • Product name

    Anti-NK-p44 antibody [EPR5060(2)] - Low endotoxin, Azide free
    See all NK-p44 primary antibodies
  • Description

    Rabbit monoclonal [EPR5060(2)] to NK-p44 - Low endotoxin, Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, Flow Cyt, ICC/IFmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human NK-p44 aa 1-100 (N terminal). The exact sequence is proprietary.

  • Positive control

    • Human lymph node lysate; K562, Jurkat, HuT-78 and Molt-4 cell lysates; K562 cells
  • General notes

    ab246801 is a carrier-free antibody designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our Low endotoxin, azide-free formats have low endotoxin level (≤ 1 EU/ml, determined by the LAL assay) and are free from azide, to achieve consistent experimental results in functional assays.

    Previously labelled as NCR2.

    Previously labelled as NCR2.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab246801 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 31 kDa.
Flow Cyt Use at an assay dependent concentration.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

ICC/IF Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function

      Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
    • Tissue specificity

      Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells.
    • Sequence similarities

      Belongs to the natural cytotoxicity receptor (NCR) family.
      Contains 1 Ig-like (immunoglobulin-like) domain.
    • Cellular localization

      Cell membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • Activating NK receptor NKp44 antibody
      • CD336 antibody
      • CD336 antigen antibody
      • dJ149M18.1 antibody
      • LY95 antibody
      • Lymphocyte antigen 95 (activating NK receptor; NK p44) antibody
      • Lymphocyte antigen 95 homolog (activating NK receptor; NK p44) antibody
      • Lymphocyte antigen 95 homolog antibody
      • Lymphocyte antigen 95, mouse, homolog of antibody
      • Natural cytotoxicity triggering receptor 2 antibody
      • Natural killer cell p44 related protein antibody
      • Natural killer cell p44-related protein antibody
      • NCR2 antibody
      • NCTR2_HUMAN antibody
      • NK cell activating receptor (NKp44) antibody
      • NK cell activating receptor antibody
      • NK cell-activating receptor antibody
      • NK p44 antibody
      • NK-p44 antibody
      • NKp44 antibody
      see all

    Images

    • Immunofluorescent analysis of K562 cells labelling NK-p44 with ab133668 at 1/100 dilution.

      This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab133668).

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

      This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab133668).

    References

    ab246801 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab246801.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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