Recombinant
RabMAb

Recombinant Anti-NKG2D antibody [EPR22935-131] (ab233557)

Overview

  • Product name

    Anti-NKG2D antibody [EPR22935-131]
    See all NKG2D primary antibodies
  • Description

    Rabbit monoclonal [EPR22935-131] to NKG2D
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Flow Cytmore details
    Unsuitable for: ICC/IF,IHC-P,IP or WB
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human NKG2D aa 50-250. The exact sequence is proprietary.
    Database link: P26718

  • Positive control

    • Flow cyt: Human PBMCs.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.01% Sodium azide
    Constituents: PBS, 40% Glycerol, 0.05% BSA
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Monoclonal
  • Clone number

    EPR22935-131
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab233557 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/600.
  • Application notes
    Is unsuitable for ICC/IF,IHC-P,IP or WB.
  • Target

    • Function

      Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.
    • Tissue specificity

      Natural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs).
    • Sequence similarities

      Contains 1 C-type lectin domain.
    • Cellular localization

      Membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • CD314 antibody
      • CD314 antigen antibody
      • D12S2489E antibody
      • Killer cell lectin like receptor subfamily K member 1 antibody
      • Killer cell lectin-like receptor subfamily K member 1 antibody
      • KLR antibody
      • KLRC4 KLRK1 readthrough antibody
      • KLRK1 antibody
      • NK cell receptor D antibody
      • NK lectin-like receptor antibody
      • NKG2 D activating NK receptor antibody
      • NKG2 D type II integral membrane protein antibody
      • NKG2-D antibody
      • NKG2-D type II integral membrane protein antibody
      • NKG2-D-activating NK receptor antibody
      • Nkg2d antibody
      • NKG2D_HUMAN antibody
      • NKLLR antibody
      • NKR P2 antibody
      • Nkrp2 antibody
      see all

    Images

    • Flow cytometric analysis of Human peripheral blood mononuclear cell (PBMC) cells labelling NKG2D with ab233557 at 1/600 (Right) compared with a Rabbit monoclonal IgG (ab172730) isotype control (Left). Goat anti rabbit IgG (Alexa Fluor® 488, ab150097) at 1/5000 dilution was used as the secondary antibody.

      Cells were stained with rabbit IgG (Left) or ab233557 (Right). Then stained with anti-CD3 conjugated to Alexa Fluor® 647 and anti-CD56 conjugated to BV421.

      Gated on CD3(-) viable cells (PMID: 26041808).

    References

    ab233557 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab233557.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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