Overview

  • Product name

    Anti-NKR-P1C antibody [PK136] (FITC)
    See all NKR-P1C primary antibodies
  • Description

    Mouse monoclonal [PK136] to NKR-P1C (FITC)
  • Host species

    Mouse
  • Conjugation

    FITC. Ex: 493nm, Em: 528nm
  • Specificity

    This antibody is specific to Mouse NKR-P1C alloantigen, Mr 80-85 kDa (39 kDa under reducing conditions).
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Tissue, cells or virus corresponding to NKR-P1C. CE mouse spleen enriched for NK-1+ cells and bone marrow cells

Properties

Applications

Our Abpromise guarantee covers the use of ab25026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Target

  • Function

    Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production.
  • Tissue specificity

    Expressed in natural killer cells.
  • Sequence similarities

    Contains 1 C-type lectin domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD161 antigen like family member C antibody
    • CD161 antigen-like family member C antibody
    • CD161c antibody
    • Killer cell lectin-like receptor subfamily B member 1C antibody
    • Klrb1c antibody
    • Klrb1f antibody
    • KLRBC_MOUSE antibody
    • Ly-55c antibody
    • Ly55c antibody
    • Lymphocyte antigen 55c antibody
    • Lymphocyte antigen 59 antibody
    • Natural killer cell surface protein P1-40 antibody
    • NK1.1 antibody
    • NKR P1.9 antibody
    • NKR P1C antibody
    • NKR-P1 40 antibody
    • NKR-P1.9 antibody
    • NKR-P1C antibody
    • NKRP1 antibody
    see all

References

This product has been referenced in:

  • McAllister CS  et al. TLR3, TRIF, and caspase 8 determine double-stranded RNA-induced epithelial cell death and survival in vivo. J Immunol 190:418-27 (2013). ICC/IF . Read more (PubMed: 23209324) »
  • Karlhofer FM & Yokoyama WM Stimulation of murine natural killer (NK) cells by a monoclonal antibody specific for the NK1.1 antigen. IL-2-activated NK cells possess additional specific stimulation pathways. J Immunol 146:3662-73 (1991). Read more (PubMed: 2026886) »
See all 5 Publications for this product

Customer reviews and Q&As

Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Mouse Tissue sections (spleen)
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: 10 mM Citrate buffer, pH 6.0
Permeabilization
No
Specification
spleen
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 30% · Temperature: 25°C
Fixative
Paraformaldehyde

Abcam user community

Verified customer

Submitted May 21 2019

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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