Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration information loading...
PurityProtein G purified
Purification notesab53237 was purified from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22 µm membrane.
Our Abpromise guarantee covers the use of ab53237 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent dilution. Detects a band of approximately 36 kDa (predicted molecular weight: 26 kDa).|
|Dot blot||Use at an assay dependent dilution.|
FunctionTranscription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Tissue specificityHighly expressed in the prostate and, at a lower level, in the testis.
Sequence similaritiesBelongs to the NK-3 homeobox family.
Contains 1 homeobox DNA-binding domain.
modificationsUbiquitinated by TOPORS; monoubiquitinated at several residues and also polyubiquitinated on single residues.
- Information by UniProt
- BAPX 2 antibody
- BAPX2 antibody
- Homeobox protein NK-3 homolog A antibody
Anti-Nkx3.1 antibody [820C3a] (ab53237) + immunised recombinant protein fragment
Predicted band size: 26 kDa
Observed band size: 36 kDa why is the actual band size different from the predicted?
ab53237 has not yet been referenced specifically in any publications.