Product nameAnti-NLRC5 antibody
See all NLRC5 primary antibodies
DescriptionRabbit polyclonal to NLRC5
Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Synthetic peptide conjugated to KLH, from the N terminus of Human NLRC5.
- Human spleen tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab117624 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 204 kDa.|
|ELISA||Use at an assay dependent concentration.|
|IHC-P||Use a concentration of 5 µg/ml.|
FunctionProbable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.
Tissue specificityExpressed in spleen, thymus, lung, brain, tonsil, heart and prostate.
Sequence similaritiesBelongs to the NLRP family.
Contains 26 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.
- Information by UniProt
- Caterpiller protein 16.1 antibody
- CLR16.1 antibody
- FLJ21709 antibody
ab117624 has been referenced in 3 publications.
- Luan P et al. NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPAR?. Nat Commun 10:2882 (2019). PubMed: 31253783
- Wang Q et al. The Long Non-coding RNA MEG3/miR-let-7c-5p Axis Regulates Ethanol-Induced Hepatic Steatosis and Apoptosis by Targeting NLRC5. Front Pharmacol 9:302 (2018). PubMed: 29692724
- Li X et al. NLRC5 expression in tumors and its role as a negative prognostic indicator in stage III non-small-cell lung cancer patients. Oncol Lett 10:1533-1540 (2015). PubMed: 26622704