Anti-NLRP10 antibody (ab105407)
Key features and details
- Rabbit polyclonal to NLRP10
- Suitable for: IHC-P, ICC/IF, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NLRP10 antibody
See all NLRP10 primary antibodies -
Description
Rabbit polyclonal to NLRP10 -
Host species
Rabbit -
Specificity
At least two isoforms of NLRP10 are known to exist; this antibody will recognize both. The antibody is predicted to not cross-react with other NLRP family members. -
Tested applications
Suitable for: IHC-P, ICC/IF, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
A 14 amino acid peptide from near the N terminus of Human NLRP10 (NP_789791).
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Positive control
- Human brain tissue lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab105407 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use at an assay dependent concentration.
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ICC/IF |
Use a concentration of 20 µg/ml.
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 75 kDa.
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Notes |
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IHC-P
Use at an assay dependent concentration. |
ICC/IF
Use a concentration of 20 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 75 kDa. |
Target
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Function
Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID. -
Tissue specificity
Widely expressed with highest levels in heart, brain and skeletal muscle. -
Sequence similarities
Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 1 NACHT domain. - Information by UniProt
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Database links
- Entrez Gene: 338322 Human
- Omim: 609662 Human
- SwissProt: Q86W26 Human
- Unigene: 449636 Human
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Alternative names
- CLR11.1 antibody
- NACHT, leucine rich repeat and PYD containing 10 antibody
- NACHT, LRR and PYD domains containing protein 10 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab105407 has not yet been referenced specifically in any publications.