Anti-NMUR1 antibody (ab121959)
Key features and details
- Rabbit polyclonal to NMUR1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NMUR1 antibody
See all NMUR1 primary antibodies -
Description
Rabbit polyclonal to NMUR1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
antigen sequence: TPLCLNCSVL PGDLYPGGAR NPMACNGSAA RGHFDPEDLN LTDEALRLKY LGPQQTELFM P, corresponding to amino acids 2-62 of Human NMUR1 (UniProt: Q9HB89).
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Positive control
- WB: RT4, Human liver and Human tonsil lysates IHC-P: Human duodenum tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab121959 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Receptor for the neuromedin-U and neuromedin-S neuropeptides. -
Tissue specificity
Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 10316 Human
- Omim: 604153 Human
- SwissProt: Q9HB89 Human
- Unigene: 471619 Human
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Alternative names
- FM-3 antibody
- G protein-coupled receptor 66 antibody
- G-protein coupled receptor 66 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab121959 has been referenced in 1 publication.
- Kuhre RE et al. Neuromedin U Does Not Act as a Decretin in Rats. Cell Metab N/A:N/A (2018). PubMed: 30449683