Overview

  • Product name

  • Description

    Rabbit polyclonal to NMUR1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    antigen sequence: TPLCLNCSVL PGDLYPGGAR NPMACNGSAA RGHFDPEDLN LTDEALRLKY LGPQQTELFM P, corresponding to amino acids 2-62 of Human NMUR1 (UniProt: Q9HB89).

  • Positive control

    • WB: RT4, Human liver and Human tonsil lysates IHC-P: Human duodenum tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab121959 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Receptor for the neuromedin-U and neuromedin-S neuropeptides.
  • Tissue specificity

    Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • FM-3 antibody
    • G protein-coupled receptor 66 antibody
    • G-protein coupled receptor 66 antibody
    • G-protein coupled receptor FM-3 antibody
    • GPR66 antibody
    • Growth hormone secretagogue receptor family Member 3 antibody
    • Neuromedin U Receptor 1 antibody
    • Neuromedin-U receptor 1 antibody
    • NMU-R1 antibody
    • NMUR1 antibody
    • NMUR1_HUMAN antibody
    see all

Images

  • ab121959, at a 1/35 dilution, staining NMUR1 in paraffin-emebedded Human duodenum tissue by Immunohistochemistry.

References

This product has been referenced in:

See 1 Publication for this product

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