N,N-Dimethyl-D-erythro-sphingosine (PKC inhibitor), Sphingosine kinase and PKC inhibitor (ab141237)

Submit a review Submit a question

Key features and details

  • Sphingosine kinase and PKC inhibitor
  • CAS Number: 119567-63-4
  • Purity: > 98%
  • Supplied in isopropanol (5 mg/ml)
  • Form / State: Liquid
  • Source: Synthetic

Overview

  • Product name

    N,N-Dimethyl-D-erythro-sphingosine (PKC inhibitor), Sphingosine kinase and PKC inhibitor

  • Description

    Sphingosine kinase and PKC inhibitor

  • Biological description

    Inhibitor of sphingosine kinase (IC50=5 µM) and PKC (IC50=12 µM). Blocks conversion of sphingosine to sphingosine-1-phosphate. Induces apoptosis and EGFR autophosphorylation. Produced via ceramide catabolism. Active in vitro.

  • Purity

    > 98%

  • CAS Number

    119567-63-4

  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (E,2S,3R)-2-(Dimethylamino)octadec-4-ene-1,3-diol

  • Molecular weight

    327.55

  • Molecular formula

    C20H41NO2

  • PubChem identifier

    5282309

  • Storage instructions

    Store at -20°C (desiccating conditions).

  • Solubility overview

    Supplied in isopropanol (5 mg/ml)

  • Handling

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)N(C)C)O

  • Source

    Synthetic

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab141237? Please let us know so that we can cite the reference in this datasheet.

ab141237 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Show All Reviews Q&A
Submit a review Submit a question

There are currently no Customer reviews or Questions for ab141237.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com