N,N-Dimethyl-D-erythro-sphingosine (PKC inhibitor), Sphingosine kinase and PKC inhibitor (ab141237)
Key features and details
- Sphingosine kinase and PKC inhibitor
- CAS Number: 119567-63-4
- Purity: > 98%
- Supplied in isopropanol (5 mg/ml)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
N,N-Dimethyl-D-erythro-sphingosine (PKC inhibitor), Sphingosine kinase and PKC inhibitor -
Description
Sphingosine kinase and PKC inhibitor -
Biological description
Inhibitor of sphingosine kinase (IC50=5 µM) and PKC (IC50=12 µM). Blocks conversion of sphingosine to sphingosine-1-phosphate. Induces apoptosis and EGFR autophosphorylation. Produced via ceramide catabolism. Active in vitro. -
Purity
> 98% -
CAS Number
119567-63-4 -
Chemical structure
Properties
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Chemical name
(E,2S,3R)-2-(Dimethylamino)octadec-4-ene-1,3-diol -
Molecular weight
327.55 -
Molecular formula
C20H41NO2 -
PubChem identifier
5282309 -
Storage instructions
Store at -20°C (desiccating conditions). -
Solubility overview
Supplied in isopropanol (5 mg/ml) -
Handling
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)N(C)C)O -
Source
Synthetic
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab141237 has not yet been referenced specifically in any publications.