Overview

  • Product name

    NNGH, Matrix metalloprotease (MMP) inhibitor
  • Description

    Broad spectrum MMP inhibitor
  • Biological description

    MMP3 (Stromelysin-1) inhibitor. Additionally shows broad spectrum inhibition activity at other MMPs. Cell permeable.
  • Purity

    > 99%
  • CAS Number

    161314-17-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Christianson CA  et al. Spinal matrix metalloproteinase 3 mediates inflammatory hyperalgesia via a tumor necrosis factor-dependent mechanism. Neuroscience 200:199-210 (2012). Read more (PubMed: 22056600) »
  • Kim EM  et al. Matrix metalloproteinase-3 is increased and participates in neuronal apoptotic signaling downstream of caspase-12 during endoplasmic reticulum stress. J Biol Chem 285:16444-52 (2010). Read more (PubMed: 20368330) »
  • Alcaraz LA  et al. Matrix metalloproteinase-inhibitor interaction: the solution structure of the catalytic domain of human matrix metalloproteinase-3 with different inhibitors. J Biol Inorg Chem 12:1197-206 (2007). Read more (PubMed: 17710450) »

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