Overview

  • Product name

    Nociceptin (1-7) (Orphanin FQ (1-7)), Endogenous ligand for ORL1
  • Description

    Bioactive fragment of nociceptin. ORL1 (NOP) receptor agonist.
  • Alternative names

    • OFQ(1-7)
    • Orphanin FQ (1-7)
  • Biological description

    Bioactive fragment of nociceptin. ORL1 (NOP) receptor agonist. Reduces nociception induced hyperalgesia and displays antinociceptive activity.
  • Purity

    > 95%
  • CAS Number

    178249-42-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Katsuyama S  et al. Antinociceptive effects of spinally administered nociceptin/orphanin FQ and its N-terminal fragments on capsaicin-induced nociception. Peptides 32:1530-5 (2011). Read more (PubMed: 21672568) »
  • Kotlinska J & Rafalski P [Nociceptin/orphanin FQ (N/OFQ)--the opioid, antiopioid or neuromodulator?]. Postepy Hig Med Dosw (Online) 58:209-15 (2004). Read more (PubMed: 15114256) »
  • Sakurada T  et al. Nociceptin (1 - 7) antagonizes nociceptin-induced hyperalgesia in mice. Br J Pharmacol 128:941-4 (1999). Read more (PubMed: 10556929) »

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