Key features and details
- Goat polyclonal to Nodal
- Suitable for: ELISA, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Nodal antibody
See all Nodal primary antibodies
DescriptionGoat polyclonal to Nodal
Tested applicationsSuitable for: ELISA, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to internal region of Human Nodal conjugated to KLH.
- Human Brain cortex and Human Placenta tissues
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab110162 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionEssential for mesoderm formation and axial patterning during embryonic development.
Involvement in diseaseDefects in NODAL are the cause of visceral heterotaxy autosomal type 5 (HTX5) [MIM:270100]. A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. Clinical features of visceral heterotaxy autosomal type 5 include situs inversus viscerum or situs ambiguus, congenital heart defect, transposition of the great vessels ventricular septal defect, atrial septal defect, truncuscommunis, and dextrocardia.
Sequence similaritiesBelongs to the TGF-beta family.
- Information by UniProt
- HTX5 antibody
- MGC138230 antibody
- Nodal antibody
ab110162 has not yet been referenced specifically in any publications.