Recombinant
RabMAb

Anti-Nogo B receptor antibody [EPR8668] (ab168351)

Overview

  • Product name
    Anti-Nogo B receptor antibody [EPR8668]
    See all Nogo B receptor primary antibodies
  • Description
    Rabbit monoclonal [EPR8668] to Nogo B receptor
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Nogo B receptor. The exact sequence is proprietary.

  • Positive control
    • A549, HUVEC and HeLa cell lysates.
  • General notes

    This antibody was developed as part of a collaboration between Epitomics, the National Institutes of Health and the lab of Qing (Robert) Miao from the Medical College of Wisconsin.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 59% PBS, 40% Glycerol, 0.5% BSA
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Monoclonal
  • Clone number
    EPR8668
  • Isotype
    IgG

Applications

Our Abpromise guarantee covers the use of ab168351 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 33 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function
      Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.
      Essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery.
    • Pathway
      Protein modification; protein glycosylation.
    • Sequence similarities
      Belongs to the UPP synthase family.
    • Cellular localization
      Endoplasmic reticulum membrane. Colocalizes with Nogo-B during VEGF and wound healing angiogenesis.
    • Information by UniProt
    • Database links
    • Alternative names
      • C6orf68 antibody
      • MGC:7199 antibody
      • NgBR antibody
      • NGBR_HUMAN antibody
      • Nogo-B receptor antibody
      • Nuclear undecaprenyl pyrophosphate synthase 1 homolog antibody
      • nus1 antibody
      • TANGO14 antibody
      • Transport and golgi organization 14 homolog antibody
      see all

    Images

    • All lanes : Anti-Nogo B receptor antibody [EPR8668] (ab168351) at 1/1000 dilution

      Lane 1 : A549 cell lysate
      Lane 2 : HUVEC cell lysate
      Lane 3 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labeled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 33 kDa

    References

    This product has been referenced in:
    • Park EJ  et al. NgBR is essential for endothelial cell glycosylation and vascular development. EMBO Rep 17:167-77 (2016). Read more (PubMed: 26755743) »
    • Zhao B  et al. Comprehensive proteome quantification reveals NgBR as a new regulator for epithelial-mesenchymal transition of breast tumor cells. J Proteomics 112C:38-52 (2014). Read more (PubMed: 25173099) »

    See all 3 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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