Nomega-Propyl-L-arginine hydrochloride, neuronal nitric oxide synthase (nNOS) inhibitor (ab146124)

Overview

  • Product name

    Nomega-Propyl-L-arginine hydrochloride, neuronal nitric oxide synthase (nNOS) inhibitor
  • Description

    Selective, reversible neuronal nitric oxide synthase (nNOS) inhibitor
  • Biological description

    Selective, reversible neuronal nitric oxide synthase (nNOS) inhibitor. Active in vivo. Nω-Propyl-L-arginine (ab146405) analog.
  • Purity

    > 98%
  • CAS Number

    137361-05-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N5-[Imino(propylamino)methyl]-L-ornithine hydrochloride
  • Molecular weight

    252.74
  • Molecular formula

    C9H20N4O2.HCl
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Cl.N[C@@H](CCCNC(=N)NCCC)C(=O)O
  • Source

    Synthetic

References

This product has been referenced in:

  • Gowda C  et al. The effects of N(omega)-propyl-L-arginine on reperfusion injury of skeletal muscle. Nitric Oxide 11:17-24 (2004). Read more (PubMed: 15350553) »
  • Klamer D  et al. The neuronal selective nitric oxide synthase inhibitor, Nomega-propyl-L-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice. Eur J Pharmacol 503:103-7 (2004). Read more (PubMed: 15496304) »
  • Cooper GR  et al. Cellular and enzymatic studies of N(omega)-propyl-l-arginine and S-ethyl-N-[4-(trifluoromethyl)phenyl]isothiourea as reversible, slowly dissociating inhibitors selective for the neuronal nitric oxide synthase isoform. Arch Biochem Biophys 375:183-94 (2000). Read more (PubMed: 10683266) »

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