Overview

  • Product name

    Norethindrone, synthetic progestin
  • Description

    Potent synthetic progestin
  • Biological description

    Potent synthetic progestin. Shows weak estrogenic and androgenic effects. Shows antiestrogenic effects at high doses. Inhibits ovulation in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    68-22-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
  • Molecular weight

    298.42
  • Molecular formula

    C20H26O2
  • PubChem identifier

    6230
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Basavaraja N  et al. Norethindrone-induced masculinization and progeny testing in guppy, Poecilia reticulata (Peters 1859). Indian J Exp Biol 52:232-6 (2014). Read more (PubMed: 24669666) »
  • Ouyang JX  et al. RNA interference mediated pten knock-down inhibit the formation of polycystic ovary. Mol Cell Biochem 380:195-202 (2013). Read more (PubMed: 23686705) »
  • Chen FP  et al. Effects of estradiol and progestogens on human breast cells: regulation of sex steroid receptors. Taiwan J Obstet Gynecol 52:365-73 (2013). Read more (PubMed: 24075375) »

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