Overview

  • Product name

  • Description

    Goat polyclonal to NPEPPS
  • Host species

    Goat
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Cow, Dog, Xenopus laevis, Chimpanzee, Macaque monkey
  • Immunogen

    Synthetic peptide:

    C-KRDAESIHQYLLQRK

    , corresponding to C terminal amino acids 899-913 of Human NPEPPS (NP_006301.3)

  • Positive control

    • Human Brain (Cerebral Cortex) lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab77643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    peptide ELISA: Use at an assay dependent dilution. Detection limit dilution: 1/4000
    WB: Use at a concentration of 0.2 - 0.5 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 103 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain.
    • Tissue specificity

      Detected in liver, epithelium of renal tubules, epithelium of small and large intestine, gastric epithelial cells, and alveoli of the lung (at protein level).
    • Sequence similarities

      Belongs to the peptidase M1 family.
    • Cellular localization

      Cytoplasm > cytosol. Nucleus.
    • Information by UniProt
    • Database links

    • Alternative names

      • AAP-S antibody
      • Aminopeptidase puromycin sensitive antibody
      • Cytosol alanyl aminopeptidase antibody
      • Metalloprotease 100 antibody
      • Metalloprotease MP100 antibody
      • MP 100 antibody
      • MP100 antibody
      • Npepps antibody
      • Psa antibody
      • PSA_HUMAN antibody
      • Puromycin sensitive aminopeptidase antibody
      • Puromycin-sensitive aminopeptidase antibody
      see all

    Images

    References

    ab77643 has not yet been referenced specifically in any publications.

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