Anti-NPFF antibody (ab10352)
Key features and details
- Rabbit polyclonal to NPFF
- Suitable for: IHC-Fr
- Reacts with: Rat
- Isotype: IgG
Overview
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Product name
Anti-NPFF antibody -
Description
Rabbit polyclonal to NPFF -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Frmore details -
Species reactivity
Reacts with: Rat -
Immunogen
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Positive control
- IHC-Fr: Rat spinal cord, Rat hypothalamus tissue
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General notes
Phe Met Arg Phe-NH2, a tetrapeptide neurotransmitter, a member of the same family of RFamide peptides as FLRFamide, sharing the same C terminal RFamide sequence. FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL Gene encodes a preproprotein where upon cleavage forms two active peptides possessing similar function.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituent: Whole serum -
Concentration information loading...
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Purity
Whole antiserum -
Primary antibody notes
Phe Met Arg Phe-NH2, a tetrapeptide neurotransmitter, a member of the same family of RFamide peptides as FLRFamide, sharing the same C terminal RFamide sequence. FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL Gene encodes a preproprotein where upon cleavage forms two active peptides possessing similar function. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab10352 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-Fr |
1/200 - 1/1000.
|
Notes |
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IHC-Fr
1/200 - 1/1000. |
Target
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Relevance
FMRFamide related peptides are morphine modulating peptides that have many physiologic effects, including the modulation of morphine induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ACCN2 and ACCN3 channels. -
Cellular localization
Secreted -
Database links
- Entrez Gene: 60337 Rat
- SwissProt: Q9WVA9 Rat
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Alternative names
- FMFRamide related peptide precursor antibody
- FMRFAL antibody
- FMRFamide related peptides precursor antibody
see all
Images
Datasheets and documents
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Datasheet download
References (5)
ab10352 has been referenced in 5 publications.
- Barcák D et al. Complex insight on microanatomy of larval "human broad tapeworm" Dibothriocephalus latus (Cestoda: Diphyllobothriidea). Parasit Vectors 12:408 (2019). PubMed: 31434579
- von Döhren J Development of the Nervous System of Carinina ochracea (Palaeonemer-tea, Nemertea). PLoS One 11:e0165649 (2016). IHC, ICC/IF . PubMed: 27792762
- Burbach JP et al. Differential expression of the FMRF gene in adult and hatchling stellate ganglia of the squid Loligo pealei. Biol Open 3:50-8 (2014). IHC . PubMed: 24326188
- Jager M et al. Multiple Sox genes are expressed in stem cells or in differentiating neuro-sensory cells in the hydrozoan Clytia hemisphaerica. Evodevo 2:12 (2011). ICC/IF . PubMed: 21631916
- Chiori R et al. Are Hox genes ancestrally involved in axial patterning? Evidence from the hydrozoan Clytia hemisphaerica (Cnidaria). PLoS ONE 4:e4231 (2009). IHC-Fr . PubMed: 19156208