• Product name

    Anti-NPFF2 Receptor antibody
    See all NPFF2 Receptor primary antibodies
  • Description

    Rabbit polyclonal to NPFF2 Receptor
  • Host species

  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Monkey, Gorilla, Common marmoset
  • Immunogen

    Synthetic peptide corresponding to Human NPFF2 Receptor (C terminal). Synthetic 18 amino acid peptide from the C terminus.
    Database link: Q9Y5X5

  • Positive control

    • Human colon and testis tissues.



Our Abpromise guarantee covers the use of ab140900 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 4 - 7 µg/ml.


  • Function

    Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
  • Tissue specificity

    Isoform 1 is abundant in placenta. Relatively highly expressed in thymus, testis, and small intestine. Expressed at low levels in several tissues including spleen, prostate, brain, heart, ovary, colon, kidney, lung, liver and pancreas and not expressed in skeletal muscle and leukocytes. Isoform 2 expression is highest in placenta (but at relatively low level compared to isoform 1). Very low level of expression in numerous tissues including adipose tissue and many brain regions. Isoform 3 is expressed in brain and heart and, at lower levels, in kidney, liver, lung and pancreas.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • G protein coupled receptor 74 antibody
    • G protein coupled receptor HLWAR 77 antibody
    • G protein coupled receptor HLWAR77 antibody
    • G-protein coupled receptor 74 antibody
    • G-protein coupled receptor HLWAR77 antibody
    • GPR 74 antibody
    • GPR74 antibody
    • HLWAR 77 antibody
    • HLWAR77 antibody
    • Neuropeptide FF 2 antibody
    • Neuropeptide FF receptor 2 antibody
    • Neuropeptide G protein coupled receptor antibody
    • Neuropeptide G-protein coupled receptor antibody
    • NPFF 2 antibody
    • NPFF R2 antibody
    • NPFF2 antibody
    • NPFF2_HUMAN antibody
    • NPFFR 2 antibody
    • Npffr2 antibody
    • NPGPR antibody
    see all


  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human colon tissue labelling NPFF2 Receptor with ab140900 at 7 µg/ml.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue labelling NPFF2 Receptor with ab140900 at 7 µg/ml.


ab140900 has not yet been referenced specifically in any publications.

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