Anti-NPR-C antibody (ab262842)

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Overview

  • Product name

    Anti-NPR-C antibody
    See all NPR-C primary antibodies

  • Description

    Rabbit polyclonal to NPR-C

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-P, ICC/IFmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant fragment corresponding to Human NPR-C aa 330-474.
    Sequence:

    PEFEKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAG YSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIAMTDVEAGTQ EVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCK


    Database link: P17342

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • IHC-P: Human kidney tissue. ICC/IF: HeLa cells

Properties

Applications

Our Abpromise guarantee covers the use of ab262842 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Fixation/Permeabilization: PFA/Triton X-100

Target

  • Function

    Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.

  • Sequence similarities

    Belongs to the ANF receptor family.

  • Cellular localization

    Membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • ANP C antibody
      • ANP-C antibody
      • ANPC antibody
      • ANPR-C antibody
      • ANPRC antibody
      • ANPRC_HUMAN antibody
      • Atrial natriuretic peptide C type receptor antibody
      • Atrial natriuretic peptide clearance receptor antibody
      • Atrial natriuretic peptide receptor 3 antibody
      • Atrial natriuretic peptide receptor type C antibody
      • Atrionatriuretic peptide receptor C antibody
      • C5orf23 antibody
      • FLJ14054 antibody
      • GUCY2B antibody
      • MGC22189 antibody
      • Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) antibody
      • Natriuretic peptide receptor C/guanylate cyclase C antibody
      • NPR 3 antibody
      • NPR C antibody
      • NPR-C antibody
      • Npr3 antibody
      • NPRC antibody
      see all

    Images

    • Immunocytochemistry/ Immunofluorescence - Anti-NPR-C antibody (ab262842)
      Immunocytochemistry/ Immunofluorescence - Anti-NPR-C antibody (ab262842)
      PFA-fixed, Triton X-100 permeabilized human HeLa cells stained for NPR-C (green) using ab262842 at 4 µg/ml in ICC/IF.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NPR-C antibody (ab262842)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NPR-C antibody (ab262842)
      Paraffin-embedded human Human kidney tissue stained for NPR-C using ab262842 at 1/50 dilution in immunohistochemical analysis.

    References

    ab262842 has not yet been referenced specifically in any publications.

    Publishing research using ab262842? Please let us know so that we can cite the reference in this datasheet.

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