Anti-NPR-C antibody - C-terminal (ab174706)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-NPR-C antibody - C-terminal
See all NPR-C primary antibodies -
Description
Goat polyclonal to NPR-C - C-terminal -
Host species
Goat -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow
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Immunogen
Synthetic peptide corresponding to Human NPR-C aa 526-539 (C terminal) (Cysteine residue). (NP_000899.1)
Sequence:ESNLGKHRELREDS
Database link: P17342 -
Positive control
- Human prostate tissue, Human placenta lysate
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General notes
This product was previously labelled as Natriuretic Peptide Receptor C
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.3
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab174706 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 10 µg/ml. | |
| WB | Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 60 kDa. |
Target
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Function
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. -
Sequence similarities
Belongs to the ANF receptor family. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 281358 Cow
- Entrez Gene: 4883 Human
- Entrez Gene: 18162 Mouse
- Entrez Gene: 25339 Rat
- Omim: 108962 Human
- SwissProt: P10730 Cow
- SwissProt: P17342 Human
- SwissProt: P70180 Mouse
see all -
Alternative names
- ANP C antibody
- ANP-C antibody
- ANPC antibody
see all
Images
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Western blot - Anti-NPR-C antibody - C-terminal (ab174706)Anti-NPR-C antibody - C-terminal (ab174706) at 3 µg + Human placenta lysate at 35 µg
Developed using the ECL technique.
Predicted band size: 60 kDaPrimary incubation was 1 hour.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NPR-C antibody - C-terminal (ab174706)Immunohistochemistry of Formalin-Fixed, Paraffin-Embedded Human prostate labeling NPR-C with ab174706 at 10 µg/ml.
Datasheets and documents
References
ab174706 has not yet been referenced specifically in any publications.
