Anti-NPR-C antibody - C-terminal (ab174706)
Key features and details
- Goat polyclonal to NPR-C - C-terminal
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NPR-C antibody - C-terminal
See all NPR-C primary antibodies -
Description
Goat polyclonal to NPR-C - C-terminal -
Host species
Goat -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow
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Immunogen
Synthetic peptide corresponding to Human NPR-C aa 526-539 (C terminal) (Cysteine residue). (NP_000899.1)
Sequence:ESNLGKHRELREDS
Database link: P17342 -
Positive control
- Human prostate tissue, Human placenta lysate
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General notes
This product was previously labelled as Natriuretic Peptide Receptor C
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab174706 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 10 µg/ml. | |
| WB | Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 60 kDa. |
Target
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Function
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. -
Sequence similarities
Belongs to the ANF receptor family. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 281358 Cow
- Entrez Gene: 4883 Human
- Entrez Gene: 18162 Mouse
- Entrez Gene: 25339 Rat
- Omim: 108962 Human
- SwissProt: P10730 Cow
- SwissProt: P17342 Human
- SwissProt: P70180 Mouse
see all -
Alternative names
- ANP C antibody
- ANP-C antibody
- ANPC antibody
see all
Images
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Western blot - Anti-NPR-C antibody - C-terminal (ab174706)Anti-NPR-C antibody - C-terminal (ab174706) at 3 µg + Human placenta lysate at 35 µg
Developed using the ECL technique.
Predicted band size: 60 kDaPrimary incubation was 1 hour.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NPR-C antibody - C-terminal (ab174706)Immunohistochemistry of Formalin-Fixed, Paraffin-Embedded Human prostate labeling NPR-C with ab174706 at 10 µg/ml.
Protocols
Datasheets and documents
References (0)
ab174706 has not yet been referenced specifically in any publications.
