Recombinant
RabMAb

Recombinant Anti-NR1D1 (phospho S55 + S59) antibody [EPR18346-44] (ab191218)

Submit a review Submit a question

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR18346-44] to NR1D1 (phospho S55 + S59)
  • Suitable for: WB, ELISA
  • Reacts with: Human

Overview

  • Product name

    Anti-NR1D1 (phospho S55 + S59) antibody [EPR18346-44]
    See all NR1D1 primary antibodies

  • Description

    Rabbit monoclonal [EPR18346-44] to NR1D1 (phospho S55 + S59)

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WB, ELISAmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Synthetic peptide within Human NR1D1 aa 50-150 (phospho S55 + S59). The exact sequence is proprietary.
    Database link: P20393

  • General notes

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

Properties

Applications

Our Abpromise guarantee covers the use of ab191218 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000. Detects a band of approximately 100 kDa (predicted molecular weight: 67 kDa).
ELISA Use at an assay dependent concentration.

Target

  • Function

    Functions as a constitutive transcriptional repressor. Possible receptor for triiodothyronine.

  • Tissue specificity

    Expressed in all tissues and cell lines examined. Expressed at high levels in some squamous carcinoma cell lines.

  • Sequence similarities

    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.

  • Domain

    Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.

  • Cellular localization

    Nucleus.
  • Information by UniProt

  • Database links

    • Alternative names

      • EAR-1 antibody
      • EAR1 antibody
      • ERBA-related 1 antibody
      • hRev antibody
      • Nr1d1 antibody
      • NR1D1_HUMAN antibody
      • Nuclear receptor Rev ErbA alpha antibody
      • Nuclear receptor subfamily 1 group D member 1 antibody
      • Rev erbAalpha antibody
      • Rev erbalpha antibody
      • Rev-erbA-alpha antibody
      • Rev-ErbAalpha antibody
      • Reverba antibody
      • THRA1 antibody
      • THRAL antibody
      • Thyroid hormone receptor, alpha like antibody
      • Thyroid hormone receptor, alpha-1- like antibody
      • V-erbA-related protein 1 antibody
      see all

    Images

    • ELISA - Anti-NR1D1 (phospho S55 + S59) antibody [EPR18346-44] (ab191218)
      ELISA - Anti-NR1D1 (phospho S55 + S59) antibody [EPR18346-44] (ab191218)

      Direct ELISA analysis of ab191218 (0-1000 ng/ml) using the following antigens: NR1D1 phospho S55 + phospho S59 peptide, NR1D1 phospho S55 peptide, NR1D1 phospho S59 peptide and NR1D1 unmodified peptide at 1000 ng/ml. An Alkaline Phosphatase-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L) at 1/2500 was used as secondary antibody. 

    References

    Publishing research using ab191218? Please let us know so that we can cite the reference in this datasheet.

    ab191218 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab191218.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com