Anti-NR3B antibody (ab106808)
Key features and details
- Goat polyclonal to NR3B
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NR3B antibody
See all NR3B primary antibodies -
Description
Goat polyclonal to NR3B -
Host species
Goat -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide:
C-EAPPHSGRPGSQ
, corresponding to C terminal amino acids 1031-1042 of Human NR3B (NP_619635.1). -
Positive control
- Human Brain (Cerebellum and Cerebral Cortex) lysates
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab106808 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab106808 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 113 kDa).
1 hour primary incubation is recommended for this product. |
Notes |
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WB
Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 113 kDa). 1 hour primary incubation is recommended for this product. |
Target
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Function
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. -
Sequence similarities
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3B/GRIN3B subfamily. -
Cellular localization
Cell membrane. Cell junction > synapse > postsynaptic cell membrane. Requires the presence of GRIN1 to be targeted at the plasma membrane. - Information by UniProt
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Database links
- Entrez Gene: 116444 Human
- Omim: 606651 Human
- SwissProt: O60391 Human
- Unigene: 660378 Human
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Form
A subunit of the N-methyl-D-aspartate (NMDA) receptor, which belongs to the superfamily of glutamate-regulated ion channels that are present in neurons throughout the central nervous system. -
Alternative names
- GluN3B antibody
- Glutamate [NMDA] receptor subunit 3B antibody
- Glutamate receptor ionotropic N methyl D aspartate 3B antibody
see all
Images
Datasheets and documents
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Datasheet download
References (0)
ab106808 has not yet been referenced specifically in any publications.