Anti-NR3B antibody (ab106808)
Key features and details
- Goat polyclonal to NR3B
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NR3B antibody
See all NR3B primary antibodies -
Description
Goat polyclonal to NR3B -
Host species
Goat -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide:
C-EAPPHSGRPGSQ
, corresponding to C terminal amino acids 1031-1042 of Human NR3B (NP_619635.1). -
Positive control
- Human Brain (Cerebellum and Cerebral Cortex) lysates
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
ab106808 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab106808 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 113 kDa). 1 hour primary incubation is recommended for this product. |
Target
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Function
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. -
Sequence similarities
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3B/GRIN3B subfamily. -
Cellular localization
Cell membrane. Cell junction > synapse > postsynaptic cell membrane. Requires the presence of GRIN1 to be targeted at the plasma membrane. - Information by UniProt
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Database links
- Entrez Gene: 116444 Human
- Omim: 606651 Human
- SwissProt: O60391 Human
- Unigene: 660378 Human
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Form
A subunit of the N-methyl-D-aspartate (NMDA) receptor, which belongs to the superfamily of glutamate-regulated ion channels that are present in neurons throughout the central nervous system. -
Alternative names
- GluN3B antibody
- Glutamate [NMDA] receptor subunit 3B antibody
- Glutamate receptor ionotropic N methyl D aspartate 3B antibody
see all
Images
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Western blot - Anti-NR3B antibody (ab106808)Anti-NR3B antibody (ab106808) at 0.5 µg/ml + Human cerebellum lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 113 kDa
Primary incubation was 1 hour.
Datasheets and documents
References (0)
ab106808 has not yet been referenced specifically in any publications.
