Overview

  • Product name
    Anti-NR3B antibody
    See all NR3B primary antibodies
  • Description
    Goat polyclonal to NR3B
  • Host species
    Goat
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    C-EAPPHSGRPGSQ

    , corresponding to C terminal amino acids 1031-1042 of Human NR3B (NP_619635.1).

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control
    • Human Brain (Cerebellum and Cerebral Cortex) lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab106808 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106808 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 113 kDa).

Target

  • Function
    NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.
  • Sequence similarities
    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3B/GRIN3B subfamily.
  • Cellular localization
    Cell membrane. Cell junction > synapse > postsynaptic cell membrane. Requires the presence of GRIN1 to be targeted at the plasma membrane.
  • Information by UniProt
  • Database links
    • Form
      A subunit of the N-methyl-D-aspartate (NMDA) receptor, which belongs to the superfamily of glutamate-regulated ion channels that are present in neurons throughout the central nervous system.
    • Alternative names
      • GluN3B antibody
      • Glutamate [NMDA] receptor subunit 3B antibody
      • Glutamate receptor ionotropic N methyl D aspartate 3B antibody
      • Glutamate receptor ionotropic NMDA 3B antibody
      • GRIN3B antibody
      • N-methyl-D-aspartate receptor subtype 3B antibody
      • NMD3B_HUMAN antibody
      • NMDA receptor subunit 3B antibody
      • NMDA type glutamate receptor subunit NR3B antibody
      • NMDAR3B antibody
      • NR3B antibody
      see all

    Images

    • Western blot - Anti-NR3B antibody (ab106808)
      Western blot - Anti-NR3B antibody (ab106808)
      Anti-NR3B antibody (ab106808) at 0.5 µg/ml + Human cerebellum lysate (in RIPA buffer) at 35 µg

      Developed using the ECL technique.

      Predicted band size: 113 kDa



      Primary incubation was 1 hour.

    References

    ab106808 has not yet been referenced specifically in any publications.

    Publishing research using ab106808? Please let us know so that we can cite the reference in this datasheet.

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