Anti-NR3B antibody (ab106808)

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Overview

  • Product name

    Anti-NR3B antibody
    See all NR3B primary antibodies

  • Description

    Goat polyclonal to NR3B

  • Host species

    Goat

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Synthetic peptide:

    C-EAPPHSGRPGSQ

    , corresponding to C terminal amino acids 1031-1042 of Human NR3B (NP_619635.1).

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • Human Brain (Cerebellum and Cerebral Cortex) lysates

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

  • Storage buffer

    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...

  • Purity

    Immunogen affinity purified

  • Purification notes

    ab106808 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106808 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 113 kDa).

Target

  • Function

    NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.

  • Sequence similarities

    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3B/GRIN3B subfamily.

  • Cellular localization

    Cell membrane. Cell junction > synapse > postsynaptic cell membrane. Requires the presence of GRIN1 to be targeted at the plasma membrane.
  • Information by UniProt

  • Database links

    • Form

      A subunit of the N-methyl-D-aspartate (NMDA) receptor, which belongs to the superfamily of glutamate-regulated ion channels that are present in neurons throughout the central nervous system.

    • Alternative names

      • GluN3B antibody
      • Glutamate [NMDA] receptor subunit 3B antibody
      • Glutamate receptor ionotropic N methyl D aspartate 3B antibody
      • Glutamate receptor ionotropic NMDA 3B antibody
      • GRIN3B antibody
      • N-methyl-D-aspartate receptor subtype 3B antibody
      • NMD3B_HUMAN antibody
      • NMDA receptor subunit 3B antibody
      • NMDA type glutamate receptor subunit NR3B antibody
      • NMDAR3B antibody
      • NR3B antibody
      see all

    Images

    • Western blot - Anti-NR3B antibody (ab106808)
      Western blot - Anti-NR3B antibody (ab106808)
      Anti-NR3B antibody (ab106808) at 0.5 µg/ml + Human cerebellum lysate (in RIPA buffer) at 35 µg

      Developed using the ECL technique.

      Predicted band size: 113 kDa



      Primary incubation was 1 hour.

    References

    ab106808 has not yet been referenced specifically in any publications.

    Publishing research using ab106808? Please let us know so that we can cite the reference in this datasheet.

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