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ab76026 has been referenced in 62 publications.

  • Liu YW  et al. Neuroprotection of quercetin on central neurons against chronic high glucose through enhancement of Nrf2/ARE/glyoxalase-1 pathway mediated by phosphorylation regulation. Biomed Pharmacother 109:2145-2154 (2019). PubMed: 30551472
  • Narda M  et al. Protective effects of a novel facial cream against environmental pollution: in vivo and in vitro assessment. Clin Cosmet Investig Dermatol 11:571-578 (2018). PubMed: 30519068
  • Kwon DH  et al. Schisandrin A suppresses lipopolysaccharide-induced inflammation and oxidative stress in RAW 264.7 macrophages by suppressing the NF-?B, MAPKs and PI3K/Akt pathways and activating Nrf2/HO-1 signaling. Int J Mol Med 41:264-274 (2018). PubMed: 29115385
  • Kuan-Hong W & Bai-Zhou L Plumbagin protects against hydrogen peroxide-induced neurotoxicity by modulating NF-?B and Nrf-2. Arch Med Sci 14:1112-1118 (2018). PubMed: 30154895
  • Ma J  et al. Baicalein protects human vitiligo melanocytes from oxidative stress through activation of NF-E2-related factor2 (Nrf2) signaling pathway. Free Radic Biol Med 129:492-503 (2018). PubMed: 30342186
  • Aspera-Werz RH  et al. Nicotine and Cotinine Inhibit Catalase and Glutathione Reductase Activity Contributing to the Impaired Osteogenesis of SCP-1 Cells Exposed to Cigarette Smoke. Oxid Med Cell Longev 2018:3172480 (2018). PubMed: 30533170
  • Relic B  et al. Serum starvation raises turnover of phosphorylated p62/SQSTM1 (Serine 349), reveals expression of proteasome and N-glycanase1 interactive protein RAD23B and sensitizes human synovial fibroblasts to BAY 11-7085-induced cell death. Oncotarget 9:35830-35843 (2018). PubMed: 30533198
  • Xu LL  et al. 3-(1H-Benzo[d]imidazol-6-yl)-5-(4-fluorophenyl)-1,2,4-oxadiazole (DDO7232), a Novel Potent Nrf2/ARE Inducer, Ameliorates DSS-Induced Murine Colitis and Protects NCM460 Cells against Oxidative Stress via ERK1/2 Phosphorylation. Oxid Med Cell Longev 2018:3271617 (2018). PubMed: 29887940
  • La Sala L  et al. Glucose-sensing microRNA-21 disrupts ROS homeostasis and impairs antioxidant responses in cellular glucose variability. Cardiovasc Diabetol 17:105 (2018). PubMed: 30037352
  • van der Waals LM  et al. Increased Levels of Oxidative Damage in Liver Metastases Compared with Corresponding Primary Colorectal Tumors: Association with Molecular Subtype and Prior Treatment. Am J Pathol 188:2369-2377 (2018). PubMed: 30031728
  • Kim EY  et al. Identification and antioxidant activity of synthetic peptides from phycobiliproteins of Pyropia yezoensis. Int J Mol Med 42:789-798 (2018). PubMed: 29717771
  • Gray NE  et al. Centella asiatica increases hippocampal synaptic density and improves memory and executive function in aged mice. Brain Behav 8:e01024 (2018). PubMed: 29920983
  • Moon H  et al. Carbon Monoxide Ameliorates 6-Hydroxydopamine-Induced Cell Death in C6 Glioma Cells. Biomol Ther (Seoul) 26:175-181 (2018). PubMed: 29429149
  • Xin Y  et al. Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway. Redox Biol 15:405-417 (2018). PubMed: 29353218
  • Lee GY  et al. Amelioration of Scopolamine-Induced Learning and Memory Impairment by a-Pinene in C57BL/6 Mice. Evid Based Complement Alternat Med 2017:4926815 (2017). PubMed: 29234406
  • Kakehashi A  et al. Progression of Hepatic Adenoma to Carcinoma in Ogg1 Mutant Mice Induced by Phenobarbital. Oxid Med Cell Longev 2017:8541064 (2017). PubMed: 28785378
  • Federti E  et al. Data demonstrating the role of peroxiredoxin 2 as important anti-oxidant system in lung homeostasis. Data Brief 15:376-381 (2017). WB . PubMed: 29034295
  • Chen L  et al. Co-Activation of PKC-d by CRIF1 Modulates Oxidative Stress in Bone Marrow Multipotent Mesenchymal Stromal Cells after Irradiation by Phosphorylating NRF2 Ser40. Theranostics 7:2634-2648 (2017). PubMed: 28819452
  • Li F  et al. Psoralen stimulates osteoblast proliferation through the activation of nuclear factor-?B-mitogen-activated protein kinase signaling. Exp Ther Med 14:2385-2391 (2017). PubMed: 28962172
  • Yong M  et al. DR2 blocker thioridazine: A promising drug for ovarian cancer therapy. Oncol Lett 14:8171-8177 (2017). PubMed: 29344260
  • Han MH  et al. Cytoprotective effects of esculetin against oxidative stress are associated with the upregulation of Nrf2-mediated NQO1 expression via the activation of the ERK pathway. Int J Mol Med 39:380-386 (2017). PubMed: 28000844
  • Olagnier D  et al. Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity. Mol Ther 25:1900-1916 (2017). PubMed: 28527723
  • Falone S  et al. Power frequency magnetic field promotes a more malignant phenotype in neuroblastoma cells via redox-related mechanisms. Sci Rep 7:11470 (2017). PubMed: 28904402
  • Kankia IH  et al. NRF2 Regulates HER1 Signaling Pathway to Modulate the Sensitivity of Ovarian Cancer Cells to Lapatinib and Erlotinib. Oxid Med Cell Longev 2017:1864578 (2017). PubMed: 29410730
  • Cui Q  et al. Curcumin ameliorates dopaminergic neuronal oxidative damage via activation of the Akt/Nrf2 pathway. Mol Med Rep 13:1381-8 (2016). PubMed: 26648392
  • Ramnarayanan S  et al. The Unfolded Protein Response Regulates Uterine Myocyte Antioxidant Responsiveness During Pregnancy. Biol Reprod 95:120 (2016). PubMed: 27733380
  • Wei Y  et al. PA-MSHA inhibits the growth of doxorubicin-resistant MCF-7/ADR human breast cancer cells by downregulating Nrf2/p62. Cancer Med 5:3520-3531 (2016). PubMed: 27758045
  • Khalil HS  et al. NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies. Oxid Med Cell Longev 2016:4148791 (2016). PubMed: 26770651
  • Arora R  et al. Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to KEAP1. Mol Cancer 15:64 (2016). WB ; Human . PubMed: 27756327
  • Wu ST  et al. Cellular effects induced by 17-ß-estradiol to reduce the survival of renal cell carcinoma cells. J Biomed Sci 23:67 (2016). WB ; Human . PubMed: 27680214
  • Dong T  et al. Pterisolic Acid B is a Nrf2 Activator by Targeting C171 within Keap1-BTB Domain. Sci Rep 6:19231 (2016). PubMed: 26757824
  • Patitucci TN & Ebert AD SMN deficiency does not induce oxidative stress in SMA iPSC-derived astrocytes or motor neurons. Hum Mol Genet 25:514-23 (2016). PubMed: 26643950
  • Jiang M  et al. BMP-driven NRF2 activation in esophageal basal cell differentiation and eosinophilic esophagitis. J Clin Invest 125:1557-68 (2015). PubMed: 25774506
  • Masuda Y  et al. The effect of Nrf2 pathway activation on human pancreatic islet cells. PLoS One 10:e0131012 (2015). IF ; Human . PubMed: 26110640
  • Kirienko NV  et al. Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 112:1821-6 (2015). WB ; Human . PubMed: 25624506
  • Gjyshi O  et al. Activated Nrf2 Interacts with Kaposi's Sarcoma-Associated Herpesvirus Latency Protein LANA-1 and Host Protein KAP1 To Mediate Global Lytic Gene Repression. J Virol 89:7874-92 (2015). PubMed: 25995248
  • Zhao XQ  et al. Promoter demethylation of nuclear factor-erythroid 2-related factor 2 gene in drug-resistant colon cancer cells. Oncol Lett 10:1287-1292 (2015). PubMed: 26622665
  • Zhang S  et al. Omeprazole induces NAD(P)H quinone oxidoreductase 1 via aryl hydrocarbon receptor-independent mechanisms: Role of the transcription factor nuclear factor erythroid 2-related factor 2. Biochem Biophys Res Commun 467:282-7 (2015). PubMed: 26441083
  • Min SY  et al. Green Tea Epigallocatechin-3-Gallate Suppresses Autoimmune Arthritis Through Indoleamine-2,3-Dioxygenase Expressing Dendritic Cells and the Nuclear Factor, Erythroid 2-Like 2 Antioxidant Pathway. J Inflamm (Lond) 12:53 (2015). WB . PubMed: 26379475
  • Stachel I  et al. Modulation of nuclear factor E2-related factor-2 (Nrf2) activation by the stress response gene immediate early response-3 (IER3) in colonic epithelial cells: a novel mechanism of cellular adaption to inflammatory stress. J Biol Chem 289:1917-29 (2014). PubMed: 24311782
  • Liu Z  et al. Tanshinone IIA suppresses cholesterol accumulation in human macrophages: role of heme oxygenase-1. J Lipid Res 55:201-13 (2014). Human . PubMed: 24302760
  • Ji L  et al. Correlation of Nrf2, NQO1, MRP1, cmyc and p53 in colorectal cancer and their relationships to clinicopathologic features and survival. Int J Clin Exp Pathol 7:1124-31 (2014). IHC-P ; Human . PubMed: 24695690
  • Sugiyama K  et al. Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus. PLoS One 9:e94460 (2014). WB, IF ; Human . PubMed: 24718268
  • Peng S  et al. In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acids. Am J Physiol Gastrointest Liver Physiol 307:G129-39 (2014). WB ; Human . PubMed: 24852569
  • Wang Y  et al. Sulforaphane reduction of testicular apoptotic cell death in diabetic mice is associated with the upregulation of Nrf2 expression and function. Am J Physiol Endocrinol Metab 307:E14-23 (2014). WB . PubMed: 24801392
  • Kim JY  et al. MicroRNA-302 induces proliferation and inhibits oxidant-induced cell death in human adipose tissue-derived mesenchymal stem cells. Cell Death Dis 5:e1385 (2014). Human . PubMed: 25144720
  • Skibba M  et al. Preventive effect of non-mitogenic acidic fibroblast growth factor on diabetes-induced testicular cell death. Reprod Toxicol 49C:136-144 (2014). Mouse . PubMed: 25150137
  • Tian H  et al. MDA-7/IL-24 inhibits Nrf2-mediated antioxidant response through activation of p38 pathway and inhibition of ERK pathway involved in cancer cell apoptosis. Cancer Gene Ther 21:416-26 (2014). PubMed: 25236495
  • Krajka-Kuzniak V  et al. The effect of resveratrol and its methylthio-derivatives on the Nrf2-ARE pathway in mouse epidermis and HaCaT keratinocytes. Cell Mol Biol Lett 19:500-16 (2014). Human . PubMed: 25169438
  • Biswas C  et al. Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses. J Biol Chem 289:26882-94 (2014). PubMed: 25107906
  • Gjyshi O  et al. Kaposi's sarcoma-associated herpesvirus induces Nrf2 during de novo infection of endothelial cells to create a microenvironment conducive to infection. PLoS Pathog 10:e1004460 (2014). PubMed: 25340789
  • Ji L  et al. Nrf2 pathway regulates multidrug-resistance-associated protein 1 in small cell lung cancer. PLoS One 8:e63404 (2013). IHC-P ; Human . PubMed: 23667609
  • Inui T  et al. Association of p62/SQSTM1 Excess and Oral Carcinogenesis. PLoS One 8:e74398 (2013). WB ; Human . PubMed: 24086340
  • Ouyang Y  et al. Carvedilol, a third-generation ß-blocker prevents oxidative stress-induced neuronal death and activates Nrf2/ARE pathway in HT22 cells. Biochem Biophys Res Commun 441:917-22 (2013). PubMed: 24216104
  • Ma T  et al. Suppression of eIF2a kinases alleviates Alzheimer's disease-related plasticity and memory deficits. Nat Neurosci 16:1299-305 (2013). WB ; Mouse . PubMed: 23933749
  • Guo W  et al. Isolation of multipotent neural stem or progenitor cells from both the dentate gyrus and subventricular zone of a single adult mouse. Nat Protoc 7:2005-12 (2012). WB ; Human . PubMed: 23080272
  • Bhaskaran N  et al. Induction of heme oxygenase-1 by chamomile protects murine macrophages against oxidative stress. Life Sci 90:1027-33 (2012). WB ; Mouse . PubMed: 22683429
  • Im JY  et al. DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway. Hum Mol Genet 21:3013-24 (2012). PubMed: 22492997
  • Li Y  et al. Mechanism of chemical activation of Nrf2. PLoS One 7:e35122 (2012). WB . PubMed: 22558124
  • Kim AD  et al. Increased glutathione synthesis following nrf2 activation by vanadyl sulfate in human chang liver cells. Int J Mol Sci 12:8878-94 (2011). WB ; Human . PubMed: 22272109
  • Murakami G  et al. Chemical library screening identifies a small molecule that downregulates SOD1 transcription for drugs to treat amyotrophic lateral sclerosis. J Biomol Screen 16:405-14 (2011). WB . PubMed: 21364087
  • Niture SK  et al. Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance. J Cell Sci 122:4452-64 (2009). WB ; Human . PubMed: 19920073

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