Key features and details
- Rabbit polyclonal to NRL
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-NRL antibody
DescriptionRabbit polyclonal to NRL
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Synthetic peptide corresponding to the N terminal region of Human NRL (UniProt P54845).
- HUVEC cell lysate
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol
PBS is without Mg2+ and Ca2+.
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab137193 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 26 kDa.|
FunctionTranscription factor which regulates the expression of several rod-specific genes, in cluding RHO and PDE6B.
Tissue specificityNeural retina.
Involvement in diseaseDefects in NRL are the cause of retinitis pigmentosa type 27 (RP27) [MIM:162080]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP27 inheritance is autosomal dominant.
Sequence similaritiesBelongs to the bZIP family.
Contains 1 bZIP domain.
- Information by UniProt
- D14S46E antibody
- Neural retina-specific leucine zipper protein antibody
- Neural retinal specific leucine zipper antibody
ab137193 has been referenced in 1 publication.
- Jamshidi F et al. Contribution of noncoding pathogenic variants to RPGRIP1-mediated inherited retinal degeneration. Genet Med 21:694-704 (2019). PubMed: 30072743