Overview

  • Product name
  • Description
    Rabbit polyclonal to NRXN3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Cow, Human
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 250 - 350 of Human NRXN3.

    Read Abcam's proprietary immunogen policy (Peptide available as ab19820.)

  • Positive control
    • This antibody gave a positive signal in the following Mouse tissue lysates; Cortex, Olfactory bulb and Cerebellum.

Properties

Applications

Our Abpromise guarantee covers the use of ab18523 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 180 kDa (predicted molecular weight: 180 kDa).

Target

  • Relevance
    NRXN3 is a neurexin protein. The neurexins are neuronal proteins that function as cell adhesion molecules during synaptogenesis and in intercellular signaling. Mammalian genomes contain just three neurexin genes. Many neurexin isoforms (>200) may be expressed through the use of two alternative promoters and alternative splicing at up to five different positions.
  • Cellular localization
    Cell Membrane
  • Database links
  • Alternative names
    • C14orf60 antibody
    • KIAA0743 antibody
    • Neurexin 3 antibody
    • Neurexin III antibody
    • Neurexin III-alpha antibody
    • Neurexin-3 antibody
    • Neurexin-3-alpha [Precursor] antibody
    • Neurexin-3-alpha antibody
    • Neurexin-III-beta antibody
    • NRXN3 antibody
    see all

Images

  • All lanes : Anti-NRXN3 antibody (ab18523) at 1 µg/ml

    Lane 1 : Mouse Cortex Tissue Lysate
    Lane 2 : Mouse Olfactory Bulb Lysate
    Lane 3 : Cerebellum Mouse Tissue Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution

    Developed using the ECL technique.

    Performed under reducing conditions.

    Predicted band size: 180 kDa
    Observed band size: 180 kDa
    Additional bands at: 100 kDa, 71 kDa. We are unsure as to the identity of these extra bands.


    Exposure time: 20 minutes

References

ab18523 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample
Mouse Tissue sections (Brain)
Specification
Brain

Dr. Sophie Pezet

Verified customer

Submitted May 09 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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