Anti-NRXN3 antibody (ab18523)
Key features and details
- Rabbit polyclonal to NRXN3
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-NRXN3 antibody
See all NRXN3 primary antibodies -
Description
Rabbit polyclonal to NRXN3 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse
Predicted to work with: Cow, Human
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Immunogen
Synthetic peptide conjugated to KLH derived from within residues 250 - 350 of Human NRXN3.
Read Abcam's proprietary immunogen policy (Peptide available as ab19820.) -
Positive control
- This antibody gave a positive signal in the following Mouse tissue lysates; Cortex, Olfactory bulb and Cerebellum.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab18523 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Detects a band of approximately 180 kDa (predicted molecular weight: 180 kDa). |
Target
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Relevance
NRXN3 is a neurexin protein. The neurexins are neuronal proteins that function as cell adhesion molecules during synaptogenesis and in intercellular signaling. Mammalian genomes contain just three neurexin genes. Many neurexin isoforms (>200) may be expressed through the use of two alternative promoters and alternative splicing at up to five different positions. -
Cellular localization
Cell Membrane -
Database links
- Entrez Gene: 614412 Cow
- Entrez Gene: 9369 Human
- Entrez Gene: 18191 Mouse
- Omim: 600567 Human
- SwissProt: Q28143 Cow
- SwissProt: Q9HDB5 Human
- SwissProt: Q9Y4C0 Human
- SwissProt: Q6P9K9 Mouse
see all -
Alternative names
- C14orf60 antibody
- KIAA0743 antibody
- Neurexin 3 antibody
see all
Images
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Western blot - Anti-NRXN3 antibody (ab18523)All lanes : Anti-NRXN3 antibody (ab18523) at 1 µg/ml
Lane 1 : Mouse Cortex Tissue Lysate
Lane 2 : Mouse Olfactory Bulb Lysate
Lane 3 : Cerebellum Mouse Tissue Lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 180 kDa
Observed band size: 180 kDa
Additional bands at: 100 kDa, 71 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 20 minutes
Datasheets and documents
References (0)
ab18523 has not yet been referenced specifically in any publications.
