Key features and details
- Rabbit polyclonal to NSFL1C
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-NSFL1C antibody
See all NSFL1C primary antibodies
DescriptionRabbit polyclonal to NSFL1C
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Recombinant fragment corresponding to Human NSFL1C aa 1-185.
Database link: Q9UNZ2
- IHC-P: Human testis and lung cancer tissues.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab234785 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/200.|
FunctionReduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity). Inhibits the activity of CTSL (in vitro).
Sequence similaritiesBelongs to the NSFL1C family.
Contains 1 SEP domain.
Contains 1 UBX domain.
modificationsPhosphorylated during mitosis. Phosphorylation inhibits interaction with Golgi membranes and is required for the fragmentation of the Golgi stacks during mitosis.
Cellular localizationNucleus. Golgi apparatus > Golgi stack. Chromosome. Predominantly nuclear in interphase cells. Bound to the axial elements of sex chromosomes in pachytene spermatocytes. A small proportion of the protein is cytoplasmic, associated with Golgi stacks.
- Information by UniProt
- DJ776F14.1 antibody
- MGC3347 antibody
- NSF1C_HUMAN antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab234785 has not yet been referenced specifically in any publications.