Key features and details
- Rabbit polyclonal to NSUN2/SAKI
- Reacts with: Mouse
- Isotype: IgG
Product nameAnti-NSUN2/SAKI antibody
See all NSUN2/SAKI primary antibodies
DescriptionRabbit polyclonal to NSUN2/SAKI
Species reactivityReacts with: Mouse
Predicted to work with: Rat, Human
Synthetic peptide corresponding to Mouse NSUN2/SAKI (internal sequence).
This product was previously labelled as NSUN2
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
Storage bufferConstituents: 1.2% Tris, 0.85% Glycine, 2% Sucrose, 95.95% Water
Concentration information loading...
PurityProtein A purified
FunctionRNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. Not able to modify tRNAs at positions 48 or 49. May act downstream of Myc to regulate epidermal cell growth and proliferation.
Sequence similaritiesBelongs to the methyltransferase superfamily. RsmB/NOP family. TRM4 subfamily.
modificationsPhosphorylated at Ser-139 by Aurora-B/STK12 during mitosis, leading to abolish methyltransferase activity and the interaction with NPM1.
Cellular localizationNucleus > nucleolus. Cytoplasm. Concentrated in the nucleolus during interphase and distributed in the perichromosome and cytoplasm during mitosis.
- Information by UniProt
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ab128243 has not yet been referenced specifically in any publications.