Recombinant Anti-NT-4 antibody [EPR9180] (ab150437)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR9180] to NT-4
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-NT-4 antibody [EPR9180]
See all NT-4 primary antibodies -
Description
Rabbit monoclonal [EPR9180] to NT-4 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: ICC/IF,IHC-P or IP -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide within Human NT-4 aa 50-150. The exact sequence is proprietary.
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Positive control
- Human prostate cancer tissue lysate, Human stomach tissue lysate
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR9180 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab150437 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 22 kDa.
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Notes |
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WB
1/1000 - 1/10000. Predicted molecular weight: 22 kDa. |
Target
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Function
Target-derived survival factor for peripheral sensory sympathetic neurons. -
Tissue specificity
Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues. -
Involvement in disease
Defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [MIM:613100]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place. -
Sequence similarities
Belongs to the NGF-beta family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 4909 Human
- Entrez Gene: 78405 Mouse
- Entrez Gene: 25730 Rat
- Omim: 162662 Human
- SwissProt: P34130 Human
- SwissProt: Q80VU4 Mouse
- SwissProt: P34131 Rat
- Unigene: 266902 Human
see all -
Alternative names
- GLC10 antibody
- GLC1O antibody
- Neurotrophic factor 4 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab150437 has not yet been referenced specifically in any publications.