RecombinantRabMAb

Recombinant Anti-NT-4 antibody [EPR9180] (ab150437)

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Western blot - Anti-NT-4 antibody [EPR9180] (ab150437)
  • Anti-NT-4 antibody [EPR9180] (ab150437)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR9180] to NT-4
  • Suitable for: WB
  • Reacts with: Human

Conjugates logo Related conjugates and formulations

Carrier Free

Overview

  • Product name

    Anti-NT-4 antibody [EPR9180]
    See all NT-4 primary antibodies

  • Description

    Rabbit monoclonal [EPR9180] to NT-4

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC/IF,IHC-P or IP

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat

  • Immunogen

    Synthetic peptide within Human NT-4 aa 50-150. The exact sequence is proprietary.

  • Positive control

    • Human prostate cancer tissue lysate, Human stomach tissue lysate

  • General notes

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

  • Storage buffer

    pH: 7.2
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant
  • Concentration information loading...

  • Purity

    Tissue culture supernatant

  • Clonality

    Monoclonal

  • Clone number

    EPR9180

  • Isotype

    IgG

  • Research areas

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab150437 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
1/1000 - 1/10000. Predicted molecular weight: 22 kDa.
Notes
WB
1/1000 - 1/10000. Predicted molecular weight: 22 kDa.
Application notes
Is unsuitable for ICC/IF,IHC-P or IP.

Target

  • Function

    Target-derived survival factor for peripheral sensory sympathetic neurons.

  • Tissue specificity

    Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.

  • Involvement in disease

    Defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [MIM:613100]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.

  • Sequence similarities

    Belongs to the NGF-beta family.

  • Cellular localization

    Secreted.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • GLC10 antibody
    • GLC1O antibody
    • Neurotrophic factor 4 antibody
    • Neurotrophic factor 5 antibody
    • Neurotrophin 4 antibody
    • Neurotrophin 4/5 antibody
    • Neurotrophin 5 (neurotrophin 4/5) antibody
    • Neurotrophin 5 antibody
    • Neurotrophin-4 antibody
    • Neurotrophin-5 antibody
    • Neutrophic factor 4 antibody
    • Neutrophic factor 5 antibody
    • NT 4 antibody
    • NT 4/5 antibody
    • NT 5 antibody
    • NT-4 antibody
    • NT-5 antibody
    • NT4 antibody
    • NT4/5 antibody
    • NT4P antibody
    • NT5 antibody
    • NTF4 antibody
    • NTF4_HUMAN antibody
    • NTF5 antibody
    see all

Images

  • Western blot - Anti-NT-4 antibody [EPR9180] (ab150437)
    Western blot - Anti-NT-4 antibody [EPR9180] (ab150437)
    All lanes : Anti-NT-4 antibody [EPR9180] (ab150437) at 1/1000 dilution

    Lane 1 : Human prostate cancer tissue lysate
    Lane 2 : Human stomach tissue lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    All lanes : Goat anti-rabbit HRP labelled antibody at 1/2000 dilution

    Predicted band size: 22 kDa

  • Anti-NT-4 antibody [EPR9180] (ab150437)
    Anti-NT-4 antibody [EPR9180] (ab150437)

References (0)

Publishing research using ab150437? Please let us know so that we can cite the reference in this datasheet.

ab150437 has not yet been referenced specifically in any publications.

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