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Neuroscience Neurology process Growth and Development Neurotrophins
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RecombinantRabMAb

Recombinant Anti-NT-4 antibody [EPR9180] (ab150437)

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Western blot - Anti-NT-4 antibody [EPR9180] (ab150437)
  • Anti-NT-4 antibody [EPR9180] (ab150437)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR9180] to NT-4
  • Suitable for: WB
  • Reacts with: Human

You may also be interested in

Secondary
Product image
Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

View more associated products

Overview

  • Product name

    Anti-NT-4 antibody [EPR9180]
    See all NT-4 primary antibodies
  • Description

    Rabbit monoclonal [EPR9180] to NT-4
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human NT-4 aa 50-150. The exact sequence is proprietary.

  • Positive control

    • Human prostate cancer tissue lysate, Human stomach tissue lysate
  • General notes

    Previously labelled as Neurotrophin 4.

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    pH: 7.2
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant
  • Concentration information loading...
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    EPR9180
  • Isotype

    IgG
  • Research areas

    • Neuroscience
    • Neurology process
    • Growth and Development
    • Neurotrophins

Associated products

  • Alternative Versions

    • Anti-NT-4 antibody [EPR9180] - BSA and Azide free (ab248989)
  • Isotype control

    • Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab172730)

Applications

Our Abpromise guarantee covers the use of ab150437 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 22 kDa.
  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function

      Target-derived survival factor for peripheral sensory sympathetic neurons.
    • Tissue specificity

      Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
    • Involvement in disease

      Defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [MIM:613100]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.
    • Sequence similarities

      Belongs to the NGF-beta family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P34130 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 4909 Human
      • Entrez Gene: 78405 Mouse
      • Entrez Gene: 25730 Rat
      • Omim: 162662 Human
      • SwissProt: P34130 Human
      • SwissProt: Q80VU4 Mouse
      • SwissProt: P34131 Rat
      • Unigene: 266902 Human
      • Unigene: 20344 Mouse
      • Unigene: 44225 Rat
      see all
    • Alternative names

      • GLC10 antibody
      • GLC1O antibody
      • Neurotrophic factor 4 antibody
      • Neurotrophic factor 5 antibody
      • Neurotrophin 4 antibody
      • Neurotrophin 4/5 antibody
      • Neurotrophin 5 (neurotrophin 4/5) antibody
      • Neurotrophin 5 antibody
      • Neurotrophin-4 antibody
      • Neurotrophin-5 antibody
      • Neutrophic factor 4 antibody
      • Neutrophic factor 5 antibody
      • NT 4 antibody
      • NT 4/5 antibody
      • NT 5 antibody
      • NT-4 antibody
      • NT-5 antibody
      • NT4 antibody
      • NT4/5 antibody
      • NT4P antibody
      • NT5 antibody
      • NTF4 antibody
      • NTF4_HUMAN antibody
      • NTF5 antibody
      see all

    Images

    • Western blot - Anti-NT-4 antibody [EPR9180] (ab150437)
      Western blot - Anti-NT-4 antibody [EPR9180] (ab150437)
      All lanes : Anti-NT-4 antibody [EPR9180] (ab150437) at 1/1000 dilution

      Lane 1 : Human prostate cancer tissue lysate
      Lane 2 : Human stomach tissue lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP labelled antibody at 1/2000 dilution

      Predicted band size: 22 kDa

    • Anti-NT-4 antibody [EPR9180] (ab150437)
      Anti-NT-4 antibody [EPR9180] (ab150437)

    Protocols

    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab150437? Please let us know so that we can cite the reference in this datasheet.

    ab150437 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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