Overview

  • Product name

    Anti-NUCB1 antibody [EPR7953]
    See all NUCB1 primary antibodies
  • Description

    Rabbit monoclonal [EPR7953] to NUCB1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IPmore details
    Unsuitable for: Flow Cyt,ICC or IHC-P
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human NUCB1. The exact sequence is proprietary.

  • Positive control

    • Human fetal lung, Human fetal heart and HeLa lysates.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Previously labelled as Nucleobindin 1.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab151705 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 54 kDa.
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IHC-P.
  • Target

    • Function

      Major calcium-binding protein of the Golgi. May have a role in calcium homeostasis.
    • Tissue specificity

      Expressed both in fetal and adult heart, lung, liver, kidney and brain, and in adult skeletal muscle, placenta and pancreas.
    • Sequence similarities

      Belongs to the nucleobindin family.
      Contains 2 EF-hand domains.
    • Domain

      The EF-hand domains are unfolded in the absence of Ca(2+) and fold upon Ca(2+) addition.
    • Post-translational
      modifications

      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localization

      Golgi apparatus > cis-Golgi network membrane. Cytoplasm. A small fraction of the protein may be cytoplasmic.
    • Information by UniProt
    • Database links

    • Alternative names

      • CALNUC antibody
      • FLJ40471 antibody
      • NUC antibody
      • NUCB 1 antibody
      • NUCB1 antibody
      • NUCB1_HUMAN antibody
      • Nucleobindin 1 antibody
      • Nucleobindin-1 antibody
      see all

    Images

    • All lanes : Anti-NUCB1 antibody [EPR7953] (ab151705) at 1/1000 dilution

      Lane 1 : Human fetal lung tissue lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : Human fetal heart tissue lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 54 kDa

    References

    ab151705 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab151705.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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