Anti-Nucleophosmin antibody [FC82291] (ab10530)

Mouse monoclonal Nucleophosmin antibody [FC82291]. Validated in WB, IP, ELISA, IHC, ICC/IF and tested in Mouse, Rat, Donkey, Hamster, Cow, Dog, Human, African green monkey. Cited in 54 publication(s).

Publishing research using ab10530? Please let us know so that we can cite the reference in this datasheet.

ab10530 has been referenced in 58 publications.

  • Liu Y  et al. Maternal DCAF13 Regulates Chromatin Tightness to Contribute to Embryonic Development. Sci Rep 9:6278 (2019). PubMed: 31000741
  • Yehia L  et al. Non-canonical role of cancer-associated mutant SEC23B in the ribosome biogenesis pathway. Hum Mol Genet 27:3154-3164 (2018). PubMed: 29893852
  • Bonora G  et al. Orientation-dependent Dxz4 contacts shape the 3D structure of the inactive X chromosome. Nat Commun 9:1445 (2018). PubMed: 29654302
  • Krastev DB  et al. Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets. Nat Commun 9:2016 (2018). PubMed: 29789535
  • Rosinska S & Filipek A Interaction of CacyBP/SIP with NPM1 and its influence on NPM1 localization and function in oxidative stress. J Cell Physiol N/A:N/A (2018). PubMed: 29806702
  • Dumbovic G  et al. A novel long non-coding RNA from NBL2 pericentromeric macrosatellite forms a perinucleolar aggregate structure in colon cancer. Nucleic Acids Res 46:5504-5524 (2018). PubMed: 29912433
  • Mata-Garrido J  et al. Persistent accumulation of unrepaired DNA damage in rat cortical neurons: nuclear organization and ChIP-seq analysis of damaged DNA. Acta Neuropathol Commun 6:68 (2018). PubMed: 30049290
  • Kim YE  et al. Quantitative Proteomic Analysis of 2D and 3D Cultured Colorectal Cancer Cells: Profiling of Tankyrase Inhibitor XAV939-Induced Proteome. Sci Rep 8:13255 (2018). PubMed: 30185973
  • Froberg JE  et al. Megadomains and superloops form dynamically but are dispensable for X-chromosome inactivation and gene escape. Nat Commun 9:5004 (2018). PubMed: 30479398
  • Posavec Marjanovic M  et al. MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption. Nat Struct Mol Biol 24:902-910 (2017). PubMed: 28991266
  • Mizielinska S  et al. Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration. Acta Neuropathol Commun 5:29 (2017). PubMed: 28420437
  • Ando K  et al. NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus. J Cell Biol 216:1795-1810 (2017). PubMed: 28432080
  • Douet J  et al. MacroH2A histone variants maintain nuclear organization and heterochromatin architecture. J Cell Sci 130:1570-1582 (2017). PubMed: 28283545
  • Ye Q  et al. Therapeutic Targeting of RNA Polymerase I With the Small-Molecule CX-5461 for Prevention of Arterial Injury-Induced Neointimal Hyperplasia. Arterioscler Thromb Vasc Biol 37:476-484 (2017). PubMed: 28062495
  • Cheung DH  et al. Nucleophosmin Interacts with PIN2/TERF1-interacting Telomerase Inhibitor 1 (PinX1) and Attenuates the PinX1 Inhibition on Telomerase Activity. Sci Rep 7:43650 (2017). IF . PubMed: 28255170
  • Chitale S & Richly H Nuclear organization of nucleotide excision repair is mediated by RING1B dependent H2A-ubiquitylation. Oncotarget 8:30870-30887 (2017). PubMed: 28416769
  • Huang M  et al. Autophagy mediates proteolysis of NPM1 and HEXIM1 and sensitivity to BET inhibition in AML cells. Oncotarget 7:74917-74930 (2016). WB ; Human . PubMed: 27732946
  • Destouches D  et al. Implication of NPM1 phosphorylation and preclinical evaluation of the nucleoprotein antagonist N6L in prostate cancer. Oncotarget 7:69397-69411 (2016). PubMed: 26993766
  • Shorbagi S & Brown IR Dynamics of the association of heat shock protein HSPA6 (Hsp70B') and HSPA1A (Hsp70-1) with stress-sensitive cytoplasmic and nuclear structures in differentiated human neuronal cells. Cell Stress Chaperones 21:993-1003 (2016). PubMed: 27527722
  • Vickers TA & Crooke ST Development of a Quantitative BRET Affinity Assay for Nucleic Acid-Protein Interactions. PLoS One 11:e0161930 (2016). WB . PubMed: 27571227
  • Garcia JS  et al. Selective Toxicity of Investigational Ixazomib for Human Leukemia Cells Expressing Mutant Cytoplasmic NPM1: Role of Reactive Oxygen Species. Clin Cancer Res 22:1978-88 (2016). PubMed: 26634271
  • Jørgensen MM  et al. Potentials and capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles 4:26048 (2015). PubMed: 25862471
  • Tancioni I  et al. FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growth. Breast Cancer Res 17:47 (2015). PubMed: 25880415
  • Arnoldo L  et al. A novel mechanism of post-translational modulation of HMGA functions by the histone chaperone nucleophosmin. Sci Rep 5:8552 (2015). WB . PubMed: 25711412
  • Nouri K  et al. Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11. PLoS One 10:e0143634 (2015). PubMed: 26624888
  • Ponti D  et al. The expression of B23 and EGR1 proteins is functionally linked in tumor cells under stress conditions. BMC Cell Biol 16:27 (2015). WB . PubMed: 26577150
  • Wang L  et al. Intracellular CD24 disrupts the ARF-NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation. Nat Commun 6:5909 (2015). PubMed: 25600590
  • Qi R  et al. The lamin-A/C-LAP2a-BAF1 protein complex regulates mitotic spindle assembly and positioning. J Cell Sci 128:2830-41 (2015). PubMed: 26092935
  • Hamilton G  et al. AKT regulates NPM dependent ARF localization and p53mut stability in tumors. Oncotarget 5:6142-67 (2014). PubMed: 25071014
  • Lührig S  et al. Lrrc34, a novel nucleolar protein, interacts with npm1 and ncl and has an impact on pluripotent stem cells. Stem Cells Dev 23:2862-74 (2014). PubMed: 24991885
  • Goudarzi KM  et al. mTOR inhibitors blunt the p53 response to nucleolar stress by regulating RPL11 and MDM2 levels. Cancer Biol Ther 15:1499-514 (2014). Human . PubMed: 25482947
  • Taha MS  et al. Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin. PLoS One 9:e91465 (2014). ICC/IF ; Human . PubMed: 24658146
  • Ponti D  et al. The transcription factor EGR1 localizes to the nucleolus and is linked to suppression of ribosomal precursor synthesis. PLoS One 9:e96037 (2014). WB ; Human . PubMed: 24787739
  • Paciaroni K  et al. Transfusion-independent ß(0)-thalassemia after bone marrow transplantation failure: proposed involvement of high parental HbF and an epigenetic mechanism. Am J Blood Res 4:27-32 (2014). WB ; Human . PubMed: 25232502
  • Khalouei S  et al. Localization of heat shock protein HSPA6 (HSP70B') to sites of transcription in cultured differentiated human neuronal cells following thermal stress. J Neurochem 131:743-54 (2014). PubMed: 25319762
  • Ding A  et al. Impact of NPM, TFF3 and TACC1 on the prognosis of patients with primary gastric cancer. PLoS One 8:e82136 (2013). IHC-P ; Human . PubMed: 24358147
  • Cong R  et al. macroH2A1 histone variant represses rDNA transcription. Nucleic Acids Res N/A:N/A (2013). PubMed: 24071584
  • Figeac N  et al. ErbB3 binding protein-1 (Ebp1) controls proliferation and myogenic differentiation of muscle stem cells. Dev Biol N/A:N/A (2013). ICC/IF ; Mouse . PubMed: 24275324
  • Bennetzen MV  et al. Acetylation dynamics of human nuclear proteins during the ionizing radiation-induced DNA damage response. Cell Cycle 12:1688-95 (2013). PubMed: 23656789
  • Lam L  et al. Regulation of subcellular distribution and oncogenic potential of nucleophosmin by plakoglobin. Oncogenesis 1:e4 (2012). PubMed: 23552556
  • Ferrando IM  et al. Identification of targets of c-Src tyrosine kinase by chemical complementation and phosphoproteomics. Mol Cell Proteomics 11:355-69 (2012). WB . PubMed: 22499769
  • Kalt I  et al. Nucleolar localization of GLTSCR2/PICT-1 is mediated by multiple unique nucleolar localization sequences. PLoS One 7:e30825 (2012). PubMed: 22292050
  • Cong R  et al. Interaction of nucleolin with ribosomal RNA genes and its role in RNA polymerase I transcription. Nucleic Acids Res 40:9441-54 (2012). PubMed: 22859736
  • Papadopoulos P  et al. A dual reporter mouse model of the human ß-globin locus: applications and limitations. PLoS One 7:e51272 (2012). WB ; Mouse . PubMed: 23272095
  • Hu R  et al. ZNF668 functions as a tumor suppressor by regulating p53 stability and function in breast cancer. Cancer Res 71:6524-34 (2011). PubMed: 21852383
  • Benedikt A  et al. The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures. Leukemia 25:135-44 (2011). WB, IP ; Human . PubMed: 21030982
  • Gallenberger M  et al. Lack of WDR36 leads to preimplantation embryonic lethality in mice and delays the formation of small subunit ribosomal RNA in human cells in vitro. Hum Mol Genet 20:422-35 (2011). ICC/IF ; Human . PubMed: 21051332
  • Doukhanine E  et al. The QKI-6 RNA binding protein regulates actin-interacting protein-1 mRNA stability during oligodendrocyte differentiation. Mol Biol Cell 21:3029-40 (2010). WB ; Human . PubMed: 20631256
  • Borg J  et al. Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin. Nat Genet 42:801-5 (2010). WB ; Human . PubMed: 20676099
  • Bandhakavi S  et al. Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response. Mol Cell Proteomics 9:403-14 (2010). PubMed: 19955088
  • Johansson H & Simonsson S Core transcription factors, Oct4, Sox2 and Nanog, individually form complexes with nucleophosmin (Npm1) to control embryonic stem (ES) cell fate determination. Aging (Albany NY) 2:815-22 (2010). WB . PubMed: 21076177
  • Song BS  et al. Nucleologenesis and embryonic genome activation are defective in interspecies cloned embryos between bovine ooplasm and rhesus monkey somatic cells. BMC Dev Biol 9:44 (2009). ICC/IF ; Cow . PubMed: 19635167
  • Hadian K  et al. Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein. J Biol Chem 284:33384-91 (2009). WB ; Human . PubMed: 19808671
  • Rees-Unwin KS  et al. Ribosome-associated nucleophosmin 1: increased expression and shuttling activity distinguishes prognostic subtypes in chronic lymphocytic leukaemia. Br J Haematol : (2009). IP ; Human . PubMed: 19961478
  • Gutiérrez L  et al. Ablation of Gata1 in adult mice results in aplastic crisis, revealing its essential role in steady-state and stress erythropoiesis. Blood 111:4375-85 (2008). PubMed: 18258797
  • Alazami AM  et al. Mutations in C2orf37, encoding a nucleolar protein, cause hypogonadism, alopecia, diabetes mellitus, mental retardation, and extrapyramidal syndrome. Am J Hum Genet 83:684-91 (2008). ICC/IF ; Human . PubMed: 19026396
  • Palaniswamy V  et al. Nucleophosmin is selectively deposited on mRNA during polyadenylation. Nat Struct Mol Biol : (2006). PubMed: 16604083
  • Kind J & van Steensel B Stochastic genome-nuclear lamina interactions: modulating roles of Lamin A and BAF. Nucleus 5:124-30 (0). IF . PubMed: 24717229

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