Overview

  • Product name

    Anti-Nucleoside phosphorylase antibody
    See all Nucleoside phosphorylase primary antibodies
  • Description

    Goat polyclonal to Nucleoside phosphorylase
  • Host species

    Goat
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Horse, Chicken, Guinea pig, Hamster, Turkey
  • Immunogen

    Synthetic peptide corresponding to Human Nucleoside phosphorylase aa 142-153 (internal sequence) (Cysteine residue). (NP_000261.2)
    Sequence:

    SGQNPLRGPNDE


    Database link: P00491

  • Positive control

    • Human tonsil and kidney tissues; Human liver lysates.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab219269 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB Use a concentration of 0.03 - 0.1 µg/ml. Predicted molecular weight: 32 kDa.

Target

  • Involvement in disease

    Defects in PNP are the cause of purine nucleoside phosphorylase deficiency (PNP deficiency) [MIM:613179]. It leads to a severe T-cell immunodeficiency with neurologic disorder in children.
  • Sequence similarities

    Belongs to the PNP/MTAP phosphorylase family.
  • Cellular localization

    Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ94043 antibody
    • FLJ97288 antibody
    • FLJ97312 antibody
    • Inosine phosphorylase antibody
    • Inosine-guanosine phosphorylase antibody
    • MGC117396 antibody
    • MGC125915 antibody
    • MGC125916 antibody
    • NP antibody
    • Np1 antibody
    • Nucleoside phosphorylase antibody
    • PNP antibody
    • Pnp1 antibody
    • PNPH_HUMAN antibody
    • PRO1837 antibody
    • PUNP antibody
    • Purine nucleoside orthophosphate ribosyltransferase antibody
    • Purine nucleoside phosphorylase 5a antibody
    • Purine nucleoside phosphorylase antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human kidney tissue labeling Nucleoside phosphorylase with ab219269 at 5 µg/ml.

  • Anti-Nucleoside phosphorylase antibody (ab219269) at 0.1 µg/ml + Human Liver lysate (in RIPA buffer) at 35 µg

    Developed using the ECL technique.

    Predicted band size: 32 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human tonsil tissue labeling Nucleoside phosphorylase with ab219269 at 5 µg/ml.

References

ab219269 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab219269.
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